Activation of 5-HT 1A Receptors in the Hypothalamic Paraventricular Nuclei Negatively Regulates Cytochrome P450 Expression and Activity in Rat Liver

Our recent work suggested a negative effect for the serotonergic innervation of the paraventricular nuclei (PVN) of the hypothalamus on growth hormone secretion and growth hormone-dependent expression of CYP2C11. The aim of our present research was to determine the effect of the activation of the 5-...

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Veröffentlicht in:Drug metabolism and disposition 2018-06, Vol.46 (6), p.786-793
Hauptverfasser: Bromek, Ewa, Rysz, Marta, Haduch, Anna, Wójcikowski, Jacek, Daniel, Władysława A
Format: Artikel
Sprache:eng
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