Hepatic Flavin-Containing Monooxygenase Gene Regulation in Different Mouse Inflammation Models

The objective of the study was to investigate the regulation of hepatic flavin-containing monooxygenases (Fmo) Fmo1, Fmo3, Fmo4, and Fmo5 in three different mouse models of inflammation, including treatment with Citrobacter rodentium, lipopolysaccharide (LPS), and dextran sulfate sodium (DSS). Quant...

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Veröffentlicht in:	Drug metabolism and disposition 2009-03, Vol.37 (3), p.462-468
Hauptverfasser:	Zhang, Jun, Chaluvadi, Madhusudana R., Reddy, Rob, Motika, Meike S., Richardson, Terrilyn A., Cashman, John R., Morgan, Edward T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Biological and medical sciences Blotting, Western Dextran Sulfate - toxicity Disease Models, Animal DNA Primers Female Gene Expression Regulation, Enzymologic Inflammation - chemically induced Inflammation - enzymology Inflammation - genetics Lipopolysaccharides - toxicity Liver - enzymology Medical sciences Mice Mice, Inbred C3H Mice, Inbred C57BL Oxygenases - genetics Pharmacology. Drug treatments RNA, Messenger - genetics Toll-Like Receptor 4 - genetics Toll-Like Receptor 4 - physiology
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