MO-FG-CAMPUS-TeP2-02: First Experiences and Perspectives in Using Direct Multicriteria Optimization (MCO) On Volumetric-Modulated Arc Therapy (VMAT) for Head and Neck Cancer
Purpose: To report the first experiences and perspectives in using direct multicriteria optimization (MCO) on volumetric-modulated arc therapy (VMAT) for head and neck (H&N) cancer. Methods: Ten prior patients with tumors in representative H&N regions were selected to evaluate direct MCO-VMA...
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| Veröffentlicht in: | Medical physics (Lancaster) 2016-06, Vol.43 (6), p.3722-3722 |
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| creator | Edgington, Samantha Cotter, Christopher Busse, Paul Crawford, Bruce Wang, Yi |
| description | Purpose:
To report the first experiences and perspectives in using direct multicriteria optimization (MCO) on volumetric-modulated arc therapy (VMAT) for head and neck (H&N) cancer.
Methods:
Ten prior patients with tumors in representative H&N regions were selected to evaluate direct MCO-VMAT in RayStation v5.0 beta. The patients were previously treated by intensity-modulated radiation therapy (IMRT) with MCO on an Elekta linear accelerator with Agility multileaf collimator. To avoid radiating eyes and shoulders, MCO-VMAT required one to three partial-arc groups, with each group consisting of single or dual arcs. All MCO-VMAT plans were approved by a radiation oncologist. The MCO-VMAT and MCO-IMRT plans were compared using V100, D5, homogeneity index (HI) and conformity index (CI) for planning target volume (PTV), Dmean and D50 for six parallel organs and Dmax for five serial organs. Patient-specific quality assurance (QA) was performed using ArcCHECK for MCO-VMAT and Matrixx for MCO-IMRT with results analyzed using gamma criteria of 3%/3mm.
Results:
MCO-VMAT provided better V100 (+0.8%) lower D5(− 0.3 Gy), lower HI (−0.27) and comparable CI (+0.05). MCO-VMAT decreased Dmean and D50 for multiple parallel organs in seven of the ten patients. On average the reduction ranged from 2.1 (larynx) to 7.6 Gy (esophagus). For the nasal cavity and nasopharynx plans significant reduction in Dmax was observed for optics (up to 11 Gy) brainstem (6.4 Gy), cord (2.1 Gy) and mandible (6.7 Gy). All MCO-VMAT and -IMRT plans passed clinical QA. MCO-VMAT required slightly longer planning time due to the more complex VMAT optimization. The net beam-on time for the MCO-VMAT plans ranged from 80 to 242 seconds, up to 9 minutes shorter than MCO-IMRT.
Conclusion:
With similar target coverage, reduced organ dose, comparable planning time, and significantly faster treatment, MCO-VMAT is very likely to become the modality of choice in RayStation v5.0 for H&N cancer. |
| doi_str_mv | 10.1118/1.4957360 |
| format | Article |
| fullrecord | <record><control><sourceid>wiley_cross</sourceid><recordid>TN_cdi_crossref_primary_10_1118_1_4957360</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>MP7360</sourcerecordid><originalsourceid>FETCH-LOGICAL-c1350-5f597a6ae6aa5dd49033d04fc7e047d636b514c57f164fa62fd80d514e78a5dd3</originalsourceid><addsrcrecordid>eNp9kcFOGzEQhq2qSE0Dh76BpV5IJYO9a3uz3KItASSWjdSE68q1Z4vLZndlOy3hnXhHHJIrnEb69f0z888g9I3RM8bY9Jyd8VxkqaSf0CjhWUp4QvPPaERpzknCqfiCvnr_l1IqU0FH6KWsyPyKFLNysfpFlrBICE0u8Nw6H_Dl0wDOQqfBY9UZvADnB9DB_ouC7fDK2-4P_mld1HC5aYPVzoZoUbgagl3bZxVs3-HTsqgmuOrwfd9u1hCc1aTszaZVAQyeOY2XD-DUsMWn9-VsOcFN7_A1KPM29Q70Iy5U3MIdo6NGtR5ODnWMVvPLZXFNbqurm2J2SzSLqYhoRJ4pqUAqJYzhOU1TQ3mjM6A8MzKVvwXjWmQNk7xRMmnMlJooQTbdGdIx-r7v2_tga69jKP2g-66LQeskkSLN4_3GaLKntOu9d9DUg7Nr5bY1o_XuGzWrD9-ILNmz_20L2_fBulwc-B97fjf87YofNH8FIbmVqA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>MO-FG-CAMPUS-TeP2-02: First Experiences and Perspectives in Using Direct Multicriteria Optimization (MCO) On Volumetric-Modulated Arc Therapy (VMAT) for Head and Neck Cancer</title><source>Wiley Online Library Journals Frontfile Complete</source><source>Alma/SFX Local Collection</source><creator>Edgington, Samantha ; Cotter, Christopher ; Busse, Paul ; Crawford, Bruce ; Wang, Yi</creator><creatorcontrib>Edgington, Samantha ; Cotter, Christopher ; Busse, Paul ; Crawford, Bruce ; Wang, Yi</creatorcontrib><description>Purpose:
To report the first experiences and perspectives in using direct multicriteria optimization (MCO) on volumetric-modulated arc therapy (VMAT) for head and neck (H&N) cancer.
Methods:
Ten prior patients with tumors in representative H&N regions were selected to evaluate direct MCO-VMAT in RayStation v5.0 beta. The patients were previously treated by intensity-modulated radiation therapy (IMRT) with MCO on an Elekta linear accelerator with Agility multileaf collimator. To avoid radiating eyes and shoulders, MCO-VMAT required one to three partial-arc groups, with each group consisting of single or dual arcs. All MCO-VMAT plans were approved by a radiation oncologist. The MCO-VMAT and MCO-IMRT plans were compared using V100, D5, homogeneity index (HI) and conformity index (CI) for planning target volume (PTV), Dmean and D50 for six parallel organs and Dmax for five serial organs. Patient-specific quality assurance (QA) was performed using ArcCHECK for MCO-VMAT and Matrixx for MCO-IMRT with results analyzed using gamma criteria of 3%/3mm.
Results:
MCO-VMAT provided better V100 (+0.8%) lower D5(− 0.3 Gy), lower HI (−0.27) and comparable CI (+0.05). MCO-VMAT decreased Dmean and D50 for multiple parallel organs in seven of the ten patients. On average the reduction ranged from 2.1 (larynx) to 7.6 Gy (esophagus). For the nasal cavity and nasopharynx plans significant reduction in Dmax was observed for optics (up to 11 Gy) brainstem (6.4 Gy), cord (2.1 Gy) and mandible (6.7 Gy). All MCO-VMAT and -IMRT plans passed clinical QA. MCO-VMAT required slightly longer planning time due to the more complex VMAT optimization. The net beam-on time for the MCO-VMAT plans ranged from 80 to 242 seconds, up to 9 minutes shorter than MCO-IMRT.
Conclusion:
With similar target coverage, reduced organ dose, comparable planning time, and significantly faster treatment, MCO-VMAT is very likely to become the modality of choice in RayStation v5.0 for H&N cancer.</description><identifier>ISSN: 0094-2405</identifier><identifier>EISSN: 2473-4209</identifier><identifier>DOI: 10.1118/1.4957360</identifier><identifier>CODEN: MPHYA6</identifier><language>eng</language><publisher>United States: American Association of Physicists in Medicine</publisher><subject>60 APPLIED LIFE SCIENCES ; Cancer ; Eyes ; Intensity modulated radiation therapy ; LINEAR ACCELERATORS ; MEDICAL PERSONNEL ; Multileaf collimators ; NECK ; NEOPLASMS ; OPTIMIZATION ; PATIENTS ; PLANNING ; QUALITY ASSURANCE ; RADIATION PROTECTION AND DOSIMETRY ; Radiation treatment ; RADIOTHERAPY</subject><ispartof>Medical physics (Lancaster), 2016-06, Vol.43 (6), p.3722-3722</ispartof><rights>American Association of Physicists in Medicine</rights><rights>2016 American Association of Physicists in Medicine</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1118%2F1.4957360$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>230,314,776,780,881,1411,27903,27904,45554</link.rule.ids><backlink>$$Uhttps://www.osti.gov/biblio/22653906$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Edgington, Samantha</creatorcontrib><creatorcontrib>Cotter, Christopher</creatorcontrib><creatorcontrib>Busse, Paul</creatorcontrib><creatorcontrib>Crawford, Bruce</creatorcontrib><creatorcontrib>Wang, Yi</creatorcontrib><title>MO-FG-CAMPUS-TeP2-02: First Experiences and Perspectives in Using Direct Multicriteria Optimization (MCO) On Volumetric-Modulated Arc Therapy (VMAT) for Head and Neck Cancer</title><title>Medical physics (Lancaster)</title><description>Purpose:
To report the first experiences and perspectives in using direct multicriteria optimization (MCO) on volumetric-modulated arc therapy (VMAT) for head and neck (H&N) cancer.
Methods:
Ten prior patients with tumors in representative H&N regions were selected to evaluate direct MCO-VMAT in RayStation v5.0 beta. The patients were previously treated by intensity-modulated radiation therapy (IMRT) with MCO on an Elekta linear accelerator with Agility multileaf collimator. To avoid radiating eyes and shoulders, MCO-VMAT required one to three partial-arc groups, with each group consisting of single or dual arcs. All MCO-VMAT plans were approved by a radiation oncologist. The MCO-VMAT and MCO-IMRT plans were compared using V100, D5, homogeneity index (HI) and conformity index (CI) for planning target volume (PTV), Dmean and D50 for six parallel organs and Dmax for five serial organs. Patient-specific quality assurance (QA) was performed using ArcCHECK for MCO-VMAT and Matrixx for MCO-IMRT with results analyzed using gamma criteria of 3%/3mm.
Results:
MCO-VMAT provided better V100 (+0.8%) lower D5(− 0.3 Gy), lower HI (−0.27) and comparable CI (+0.05). MCO-VMAT decreased Dmean and D50 for multiple parallel organs in seven of the ten patients. On average the reduction ranged from 2.1 (larynx) to 7.6 Gy (esophagus). For the nasal cavity and nasopharynx plans significant reduction in Dmax was observed for optics (up to 11 Gy) brainstem (6.4 Gy), cord (2.1 Gy) and mandible (6.7 Gy). All MCO-VMAT and -IMRT plans passed clinical QA. MCO-VMAT required slightly longer planning time due to the more complex VMAT optimization. The net beam-on time for the MCO-VMAT plans ranged from 80 to 242 seconds, up to 9 minutes shorter than MCO-IMRT.
Conclusion:
With similar target coverage, reduced organ dose, comparable planning time, and significantly faster treatment, MCO-VMAT is very likely to become the modality of choice in RayStation v5.0 for H&N cancer.</description><subject>60 APPLIED LIFE SCIENCES</subject><subject>Cancer</subject><subject>Eyes</subject><subject>Intensity modulated radiation therapy</subject><subject>LINEAR ACCELERATORS</subject><subject>MEDICAL PERSONNEL</subject><subject>Multileaf collimators</subject><subject>NECK</subject><subject>NEOPLASMS</subject><subject>OPTIMIZATION</subject><subject>PATIENTS</subject><subject>PLANNING</subject><subject>QUALITY ASSURANCE</subject><subject>RADIATION PROTECTION AND DOSIMETRY</subject><subject>Radiation treatment</subject><subject>RADIOTHERAPY</subject><issn>0094-2405</issn><issn>2473-4209</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNp9kcFOGzEQhq2qSE0Dh76BpV5IJYO9a3uz3KItASSWjdSE68q1Z4vLZndlOy3hnXhHHJIrnEb69f0z888g9I3RM8bY9Jyd8VxkqaSf0CjhWUp4QvPPaERpzknCqfiCvnr_l1IqU0FH6KWsyPyKFLNysfpFlrBICE0u8Nw6H_Dl0wDOQqfBY9UZvADnB9DB_ouC7fDK2-4P_mld1HC5aYPVzoZoUbgagl3bZxVs3-HTsqgmuOrwfd9u1hCc1aTszaZVAQyeOY2XD-DUsMWn9-VsOcFN7_A1KPM29Q70Iy5U3MIdo6NGtR5ODnWMVvPLZXFNbqurm2J2SzSLqYhoRJ4pqUAqJYzhOU1TQ3mjM6A8MzKVvwXjWmQNk7xRMmnMlJooQTbdGdIx-r7v2_tga69jKP2g-66LQeskkSLN4_3GaLKntOu9d9DUg7Nr5bY1o_XuGzWrD9-ILNmz_20L2_fBulwc-B97fjf87YofNH8FIbmVqA</recordid><startdate>201606</startdate><enddate>201606</enddate><creator>Edgington, Samantha</creator><creator>Cotter, Christopher</creator><creator>Busse, Paul</creator><creator>Crawford, Bruce</creator><creator>Wang, Yi</creator><general>American Association of Physicists in Medicine</general><scope>AAYXX</scope><scope>CITATION</scope><scope>OTOTI</scope></search><sort><creationdate>201606</creationdate><title>MO-FG-CAMPUS-TeP2-02: First Experiences and Perspectives in Using Direct Multicriteria Optimization (MCO) On Volumetric-Modulated Arc Therapy (VMAT) for Head and Neck Cancer</title><author>Edgington, Samantha ; Cotter, Christopher ; Busse, Paul ; Crawford, Bruce ; Wang, Yi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1350-5f597a6ae6aa5dd49033d04fc7e047d636b514c57f164fa62fd80d514e78a5dd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>60 APPLIED LIFE SCIENCES</topic><topic>Cancer</topic><topic>Eyes</topic><topic>Intensity modulated radiation therapy</topic><topic>LINEAR ACCELERATORS</topic><topic>MEDICAL PERSONNEL</topic><topic>Multileaf collimators</topic><topic>NECK</topic><topic>NEOPLASMS</topic><topic>OPTIMIZATION</topic><topic>PATIENTS</topic><topic>PLANNING</topic><topic>QUALITY ASSURANCE</topic><topic>RADIATION PROTECTION AND DOSIMETRY</topic><topic>Radiation treatment</topic><topic>RADIOTHERAPY</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Edgington, Samantha</creatorcontrib><creatorcontrib>Cotter, Christopher</creatorcontrib><creatorcontrib>Busse, Paul</creatorcontrib><creatorcontrib>Crawford, Bruce</creatorcontrib><creatorcontrib>Wang, Yi</creatorcontrib><collection>CrossRef</collection><collection>OSTI.GOV</collection><jtitle>Medical physics (Lancaster)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Edgington, Samantha</au><au>Cotter, Christopher</au><au>Busse, Paul</au><au>Crawford, Bruce</au><au>Wang, Yi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>MO-FG-CAMPUS-TeP2-02: First Experiences and Perspectives in Using Direct Multicriteria Optimization (MCO) On Volumetric-Modulated Arc Therapy (VMAT) for Head and Neck Cancer</atitle><jtitle>Medical physics (Lancaster)</jtitle><date>2016-06</date><risdate>2016</risdate><volume>43</volume><issue>6</issue><spage>3722</spage><epage>3722</epage><pages>3722-3722</pages><issn>0094-2405</issn><eissn>2473-4209</eissn><coden>MPHYA6</coden><abstract>Purpose:
To report the first experiences and perspectives in using direct multicriteria optimization (MCO) on volumetric-modulated arc therapy (VMAT) for head and neck (H&N) cancer.
Methods:
Ten prior patients with tumors in representative H&N regions were selected to evaluate direct MCO-VMAT in RayStation v5.0 beta. The patients were previously treated by intensity-modulated radiation therapy (IMRT) with MCO on an Elekta linear accelerator with Agility multileaf collimator. To avoid radiating eyes and shoulders, MCO-VMAT required one to three partial-arc groups, with each group consisting of single or dual arcs. All MCO-VMAT plans were approved by a radiation oncologist. The MCO-VMAT and MCO-IMRT plans were compared using V100, D5, homogeneity index (HI) and conformity index (CI) for planning target volume (PTV), Dmean and D50 for six parallel organs and Dmax for five serial organs. Patient-specific quality assurance (QA) was performed using ArcCHECK for MCO-VMAT and Matrixx for MCO-IMRT with results analyzed using gamma criteria of 3%/3mm.
Results:
MCO-VMAT provided better V100 (+0.8%) lower D5(− 0.3 Gy), lower HI (−0.27) and comparable CI (+0.05). MCO-VMAT decreased Dmean and D50 for multiple parallel organs in seven of the ten patients. On average the reduction ranged from 2.1 (larynx) to 7.6 Gy (esophagus). For the nasal cavity and nasopharynx plans significant reduction in Dmax was observed for optics (up to 11 Gy) brainstem (6.4 Gy), cord (2.1 Gy) and mandible (6.7 Gy). All MCO-VMAT and -IMRT plans passed clinical QA. MCO-VMAT required slightly longer planning time due to the more complex VMAT optimization. The net beam-on time for the MCO-VMAT plans ranged from 80 to 242 seconds, up to 9 minutes shorter than MCO-IMRT.
Conclusion:
With similar target coverage, reduced organ dose, comparable planning time, and significantly faster treatment, MCO-VMAT is very likely to become the modality of choice in RayStation v5.0 for H&N cancer.</abstract><cop>United States</cop><pub>American Association of Physicists in Medicine</pub><doi>10.1118/1.4957360</doi><tpages>1</tpages></addata></record> |
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| source | Wiley Online Library Journals Frontfile Complete; Alma/SFX Local Collection |
| subjects | 60 APPLIED LIFE SCIENCES Cancer Eyes Intensity modulated radiation therapy LINEAR ACCELERATORS MEDICAL PERSONNEL Multileaf collimators NECK NEOPLASMS OPTIMIZATION PATIENTS PLANNING QUALITY ASSURANCE RADIATION PROTECTION AND DOSIMETRY Radiation treatment RADIOTHERAPY |
| title | MO-FG-CAMPUS-TeP2-02: First Experiences and Perspectives in Using Direct Multicriteria Optimization (MCO) On Volumetric-Modulated Arc Therapy (VMAT) for Head and Neck Cancer |
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