SU‐E‐T‐709: Spatial Resolution Requirements for Fragment Identification in a Carbon Ion Spread Out Bragg Peak

Purpose: To determine spatial resolution for detectors used to identify charged fragments in a carbon ion therapy spread out Bragg peak. Methods: The Geant4 Monte Carlo toolkit was used to simulate a 2 × 2 cm2 broad beam of carbon ions incident on a 30 × 30 × 12 cm3 water phantom. The carbon ion ene...

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Veröffentlicht in:Medical physics (Lancaster) 2015-06, Vol.42 (6Part23), p.3500-3500
Hauptverfasser: McBeth, R, Borak, T
Format: Artikel
Sprache:eng
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Zusammenfassung:Purpose: To determine spatial resolution for detectors used to identify charged fragments in a carbon ion therapy spread out Bragg peak. Methods: The Geant4 Monte Carlo toolkit was used to simulate a 2 × 2 cm2 broad beam of carbon ions incident on a 30 × 30 × 12 cm3 water phantom. The carbon ion energies ranged from 165 MeV/n to 220 MeV/n and intensities were selected in order to simulate a SOBP extending from 6 to 10 cm in depth. Scoring of secondary fragments was performed for different pixel sizes at 3 depths in water. The analysis was designed to identify situations where two or more fragments intercept a pixel coincidently. Results: Initial results show that increased depths in the phantom require smaller pixel sizes due to increases in fragment population. At a pixel size of 1 × 1 cm2, a detector pixel was intercepted by two or more particles 16%, 14% and 30% percent of the time at depths of 6, 8 and 10 cm respectively. The probability of coincident hits decreases with smaller pixel size. At a pixel size of 0.05 × 0.05 cm2 a detector pixel was intercepted by two or more particles 0.7%, 0.9%, and 2% of the time at depths of 6, 8 and 10 cm respectively. Conclusion: Accurate characterization of carbon ion beams requires the consideration of secondary charged particles that have different radiobiological effectiveness. A method for accurate identification in a clinical setting could lead to improved models for treatment planning. This work investigated the spatial resolution requirements for a detector that could be used to perform secondary fragment identification in a spread out Bragg peak. These preliminary results show that detectors with pixel size on the order of 0.5 × 0.5 mm2 may be sufficient. This work was supported through research grant NNX13AD19G for Early Stage Innovations (ESI) administered through the NASA Space Technology Research Grants Program. No conflict of interest.
ISSN:0094-2405
2473-4209
DOI:10.1118/1.4925073