Design and characterization of a spatially distributed multibeam field emission x-ray source for stationary digital breast tomosynthesis
Digital breast tomosynthesis (DBT) is a limited angle computed tomography technique that can distinguish tumors from its overlying breast tissues and has potentials for detection of cancers at a smaller size and earlier stage. Current prototype DBT scanners are based on the regular full-field digita...
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description | Digital breast tomosynthesis (DBT) is a limited angle computed tomography technique that can distinguish tumors from its overlying breast tissues and has potentials for detection of cancers at a smaller size and earlier stage. Current prototype DBT scanners are based on the regular full-field digital mammography systems and require partial isocentric motion of an x-ray tube over certain angular range to record the projection views. This prolongs the scanning time and, in turn, degrades the imaging quality due to motion blur. To mitigate the above limitations, the concept of a stationary DBT (s-DBT) scanner has been recently proposed based on the newly developed spatially distributed multibeam field emission x-ray (MBFEX) source technique using the carbon nanotube. The purpose of this article is to evaluate the performance of the 25-beam MBFEX source array that has been designed and fabricated for the s-DBT system. The s-DBT system records all the projection images by electronically activating the multiple x-ray beams from different viewing angles without any mechanical motion. The configuration of the MBFEX source is close to the published values from the Siemens Mammomat system. The key issues including the x-ray flux, focal spot size, spatial resolution, scanning time, beam-to-beam consistency, and reliability are evaluated using the standard procedures. In this article, the authors describe the design and performance of a distributed x-ray source array specifically designed for the s-DBT system. They evaluate the emission current, current variation, lifetime, and focal spot sizes of the source array. An emission current of up to 18 mA was obtained at
0.5
×
0.3
mm
effective focal spot size. The experimentally measured focal spot sizes are comparable to that of a typical commercial mammography tube without motion blurring. Trade-off between the system spatial resolution, x-ray flux, and scanning time are also discussed. Projection images of a breast phantom were collected using the x-ray source array from 25 different viewing angles without motion. These preliminary results demonstrate the feasibility of the proposed s-DBT scanner. The technology has the potential to increase the resolution and reduce the imaging time for DBT. With the present design of 25 views, they demonstrated experimentally the feasibility of achieving 11 s scanning time at full detector resolution with
0.5
×
0.3
mm
source resolution without motion blur. The flexibility in config |
doi_str_mv | 10.1118/1.3213520 |
format | Article |
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0.5
×
0.3
mm
effective focal spot size. The experimentally measured focal spot sizes are comparable to that of a typical commercial mammography tube without motion blurring. Trade-off between the system spatial resolution, x-ray flux, and scanning time are also discussed. Projection images of a breast phantom were collected using the x-ray source array from 25 different viewing angles without motion. These preliminary results demonstrate the feasibility of the proposed s-DBT scanner. The technology has the potential to increase the resolution and reduce the imaging time for DBT. With the present design of 25 views, they demonstrated experimentally the feasibility of achieving 11 s scanning time at full detector resolution with
0.5
×
0.3
mm
source resolution without motion blur. The flexibility in configuration of the x-ray source array will also allow system designers to consider imaging geometries that are difficult to achieve with the conventional single-source rotating approach.</description><identifier>ISSN: 0094-2405</identifier><identifier>EISSN: 2473-4209</identifier><identifier>EISSN: 0094-2405</identifier><identifier>DOI: 10.1118/1.3213520</identifier><identifier>PMID: 19928069</identifier><identifier>CODEN: MPHYA6</identifier><language>eng</language><publisher>United States: American Association of Physicists in Medicine</publisher><subject>biological organs ; biomedical imaging ; BIOMEDICAL RADIOGRAPHY ; breast imaging ; cancer ; carbon nanotube ; carbon nanotubes ; Cathodes ; CHEST ; Computed tomography ; Computer-Aided Design ; computerised tomography ; COMPUTERIZED TOMOGRAPHY ; DESIGN ; Digital mammography ; Electric currents ; Electrodes ; Equipment Design ; Equipment Failure Analysis ; field emission ; INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY ; Mammography ; Mammography - instrumentation ; Medical imaging ; Medical X‐ray imaging ; Modulation transfer functions ; phantoms ; RADIATION DETECTION ; Radiation Imaging Physics ; Radiographic Image Enhancement - instrumentation ; RADIOLOGY AND NUCLEAR MEDICINE ; Radiometry ; Reproducibility of Results ; Scattering, Radiation ; Sensitivity and Specificity ; SPATIAL RESOLUTION ; Tomography, X-Ray Computed - instrumentation ; tomosynthesis ; Transducers ; tumours ; Vacuum tubes ; X RADIATION ; x-ray ; X-RAY SOURCES ; X-Rays ; X‐ray applications ; X‐ray detectors ; X‐ray imaging</subject><ispartof>Medical physics (Lancaster), 2009-10, Vol.36 (10), p.4389-4399</ispartof><rights>American Association of Physicists in Medicine</rights><rights>2009 American Association of Physicists in Medicine</rights><rights>Copyright © 2009 American Association of Physicists in Medicine 2009 American Association of Physicists in Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5650-5230d8c9675de838b59548f25e95c97c8d203aed0615445675ad5396fb149d913</citedby><cites>FETCH-LOGICAL-c5650-5230d8c9675de838b59548f25e95c97c8d203aed0615445675ad5396fb149d913</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1118%2F1.3213520$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1118%2F1.3213520$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>230,314,777,781,882,1412,27905,27906,45555,45556</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19928069$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/22102098$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Qian, Xin</creatorcontrib><creatorcontrib>Rajaram, Ramya</creatorcontrib><creatorcontrib>Calderon-Colon, Xiomara</creatorcontrib><creatorcontrib>Yang, Guang</creatorcontrib><creatorcontrib>Phan, Tuyen</creatorcontrib><creatorcontrib>Lalush, David S.</creatorcontrib><creatorcontrib>Lu, Jianping</creatorcontrib><creatorcontrib>Zhou, Otto</creatorcontrib><title>Design and characterization of a spatially distributed multibeam field emission x-ray source for stationary digital breast tomosynthesis</title><title>Medical physics (Lancaster)</title><addtitle>Med Phys</addtitle><description>Digital breast tomosynthesis (DBT) is a limited angle computed tomography technique that can distinguish tumors from its overlying breast tissues and has potentials for detection of cancers at a smaller size and earlier stage. Current prototype DBT scanners are based on the regular full-field digital mammography systems and require partial isocentric motion of an x-ray tube over certain angular range to record the projection views. This prolongs the scanning time and, in turn, degrades the imaging quality due to motion blur. To mitigate the above limitations, the concept of a stationary DBT (s-DBT) scanner has been recently proposed based on the newly developed spatially distributed multibeam field emission x-ray (MBFEX) source technique using the carbon nanotube. The purpose of this article is to evaluate the performance of the 25-beam MBFEX source array that has been designed and fabricated for the s-DBT system. The s-DBT system records all the projection images by electronically activating the multiple x-ray beams from different viewing angles without any mechanical motion. The configuration of the MBFEX source is close to the published values from the Siemens Mammomat system. The key issues including the x-ray flux, focal spot size, spatial resolution, scanning time, beam-to-beam consistency, and reliability are evaluated using the standard procedures. In this article, the authors describe the design and performance of a distributed x-ray source array specifically designed for the s-DBT system. They evaluate the emission current, current variation, lifetime, and focal spot sizes of the source array. An emission current of up to 18 mA was obtained at
0.5
×
0.3
mm
effective focal spot size. The experimentally measured focal spot sizes are comparable to that of a typical commercial mammography tube without motion blurring. Trade-off between the system spatial resolution, x-ray flux, and scanning time are also discussed. Projection images of a breast phantom were collected using the x-ray source array from 25 different viewing angles without motion. These preliminary results demonstrate the feasibility of the proposed s-DBT scanner. The technology has the potential to increase the resolution and reduce the imaging time for DBT. With the present design of 25 views, they demonstrated experimentally the feasibility of achieving 11 s scanning time at full detector resolution with
0.5
×
0.3
mm
source resolution without motion blur. The flexibility in configuration of the x-ray source array will also allow system designers to consider imaging geometries that are difficult to achieve with the conventional single-source rotating approach.</description><subject>biological organs</subject><subject>biomedical imaging</subject><subject>BIOMEDICAL RADIOGRAPHY</subject><subject>breast imaging</subject><subject>cancer</subject><subject>carbon nanotube</subject><subject>carbon nanotubes</subject><subject>Cathodes</subject><subject>CHEST</subject><subject>Computed tomography</subject><subject>Computer-Aided Design</subject><subject>computerised tomography</subject><subject>COMPUTERIZED TOMOGRAPHY</subject><subject>DESIGN</subject><subject>Digital mammography</subject><subject>Electric currents</subject><subject>Electrodes</subject><subject>Equipment Design</subject><subject>Equipment Failure Analysis</subject><subject>field emission</subject><subject>INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY</subject><subject>Mammography</subject><subject>Mammography - instrumentation</subject><subject>Medical imaging</subject><subject>Medical X‐ray imaging</subject><subject>Modulation transfer functions</subject><subject>phantoms</subject><subject>RADIATION DETECTION</subject><subject>Radiation Imaging Physics</subject><subject>Radiographic Image Enhancement - instrumentation</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>Radiometry</subject><subject>Reproducibility of Results</subject><subject>Scattering, Radiation</subject><subject>Sensitivity and Specificity</subject><subject>SPATIAL RESOLUTION</subject><subject>Tomography, X-Ray Computed - instrumentation</subject><subject>tomosynthesis</subject><subject>Transducers</subject><subject>tumours</subject><subject>Vacuum tubes</subject><subject>X RADIATION</subject><subject>x-ray</subject><subject>X-RAY SOURCES</subject><subject>X-Rays</subject><subject>X‐ray applications</subject><subject>X‐ray detectors</subject><subject>X‐ray imaging</subject><issn>0094-2405</issn><issn>2473-4209</issn><issn>0094-2405</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNksuKFDEUhgtRnHZ04QtIwIUo1JhrVWUjyHiFEV3oOqSSU92RVKVNUqPtE_jYpruLcVyMuAohX778OedU1UOCzwgh3XNyxihhguJb1YryltWcYnm7WmEseU05FifVvZS-YowbJvDd6oRISTvcyFX16xUkt56QniwyGx21yRDdT51dmFAYkEZpWzba-x2yLuXo-jmDRePss-tBj2hw4C2C0aW0v_OjjnqHUpijATSEiFI-yHTcC9Yua4_6CDpllMMY0m7KmxIh3a_uDNoneLCsp9WXN68_n7-rLz6-fX_-8qI2ohG4FpRh2xnZtMJCx7peSMG7gQqQwsjWdJZipsHihgjORcG0FUw2Q0-4tJKw0-rF0bud-xGsgSlH7dU2urFEVEE79ffJ5DZqHS4VbVvSElwEj4-CkLJTybgMZmPCNIHJilKCS-27Qj1Znonh2wwpq1IgA97rCcKcVMs44Q05BHp6JE0MKUUYrrIQrPbtVUQt7S3so-vh_5BLPwtQH4HvzsPuZpP68GkRLtXY_-PQp5vvHCdFlUlRV5NSBM_-W_Av-DLEa-m2dmC_Abkc4Xc</recordid><startdate>200910</startdate><enddate>200910</enddate><creator>Qian, Xin</creator><creator>Rajaram, Ramya</creator><creator>Calderon-Colon, Xiomara</creator><creator>Yang, Guang</creator><creator>Phan, Tuyen</creator><creator>Lalush, David S.</creator><creator>Lu, Jianping</creator><creator>Zhou, Otto</creator><general>American Association of Physicists in Medicine</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>OTOTI</scope><scope>5PM</scope></search><sort><creationdate>200910</creationdate><title>Design and characterization of a spatially distributed multibeam field emission x-ray source for stationary digital breast tomosynthesis</title><author>Qian, Xin ; Rajaram, Ramya ; Calderon-Colon, Xiomara ; Yang, Guang ; Phan, Tuyen ; Lalush, David S. ; Lu, Jianping ; Zhou, Otto</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5650-5230d8c9675de838b59548f25e95c97c8d203aed0615445675ad5396fb149d913</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>biological organs</topic><topic>biomedical imaging</topic><topic>BIOMEDICAL RADIOGRAPHY</topic><topic>breast imaging</topic><topic>cancer</topic><topic>carbon nanotube</topic><topic>carbon nanotubes</topic><topic>Cathodes</topic><topic>CHEST</topic><topic>Computed tomography</topic><topic>Computer-Aided Design</topic><topic>computerised tomography</topic><topic>COMPUTERIZED TOMOGRAPHY</topic><topic>DESIGN</topic><topic>Digital mammography</topic><topic>Electric currents</topic><topic>Electrodes</topic><topic>Equipment Design</topic><topic>Equipment Failure Analysis</topic><topic>field emission</topic><topic>INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY</topic><topic>Mammography</topic><topic>Mammography - instrumentation</topic><topic>Medical imaging</topic><topic>Medical X‐ray imaging</topic><topic>Modulation transfer functions</topic><topic>phantoms</topic><topic>RADIATION DETECTION</topic><topic>Radiation Imaging Physics</topic><topic>Radiographic Image Enhancement - instrumentation</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>Radiometry</topic><topic>Reproducibility of Results</topic><topic>Scattering, Radiation</topic><topic>Sensitivity and Specificity</topic><topic>SPATIAL RESOLUTION</topic><topic>Tomography, X-Ray Computed - instrumentation</topic><topic>tomosynthesis</topic><topic>Transducers</topic><topic>tumours</topic><topic>Vacuum tubes</topic><topic>X RADIATION</topic><topic>x-ray</topic><topic>X-RAY SOURCES</topic><topic>X-Rays</topic><topic>X‐ray applications</topic><topic>X‐ray detectors</topic><topic>X‐ray imaging</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Qian, Xin</creatorcontrib><creatorcontrib>Rajaram, Ramya</creatorcontrib><creatorcontrib>Calderon-Colon, Xiomara</creatorcontrib><creatorcontrib>Yang, Guang</creatorcontrib><creatorcontrib>Phan, Tuyen</creatorcontrib><creatorcontrib>Lalush, David S.</creatorcontrib><creatorcontrib>Lu, Jianping</creatorcontrib><creatorcontrib>Zhou, Otto</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>OSTI.GOV</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Medical physics (Lancaster)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Qian, Xin</au><au>Rajaram, Ramya</au><au>Calderon-Colon, Xiomara</au><au>Yang, Guang</au><au>Phan, Tuyen</au><au>Lalush, David S.</au><au>Lu, Jianping</au><au>Zhou, Otto</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Design and characterization of a spatially distributed multibeam field emission x-ray source for stationary digital breast tomosynthesis</atitle><jtitle>Medical physics (Lancaster)</jtitle><addtitle>Med Phys</addtitle><date>2009-10</date><risdate>2009</risdate><volume>36</volume><issue>10</issue><spage>4389</spage><epage>4399</epage><pages>4389-4399</pages><issn>0094-2405</issn><eissn>2473-4209</eissn><eissn>0094-2405</eissn><coden>MPHYA6</coden><abstract>Digital breast tomosynthesis (DBT) is a limited angle computed tomography technique that can distinguish tumors from its overlying breast tissues and has potentials for detection of cancers at a smaller size and earlier stage. Current prototype DBT scanners are based on the regular full-field digital mammography systems and require partial isocentric motion of an x-ray tube over certain angular range to record the projection views. This prolongs the scanning time and, in turn, degrades the imaging quality due to motion blur. To mitigate the above limitations, the concept of a stationary DBT (s-DBT) scanner has been recently proposed based on the newly developed spatially distributed multibeam field emission x-ray (MBFEX) source technique using the carbon nanotube. The purpose of this article is to evaluate the performance of the 25-beam MBFEX source array that has been designed and fabricated for the s-DBT system. The s-DBT system records all the projection images by electronically activating the multiple x-ray beams from different viewing angles without any mechanical motion. The configuration of the MBFEX source is close to the published values from the Siemens Mammomat system. The key issues including the x-ray flux, focal spot size, spatial resolution, scanning time, beam-to-beam consistency, and reliability are evaluated using the standard procedures. In this article, the authors describe the design and performance of a distributed x-ray source array specifically designed for the s-DBT system. They evaluate the emission current, current variation, lifetime, and focal spot sizes of the source array. An emission current of up to 18 mA was obtained at
0.5
×
0.3
mm
effective focal spot size. The experimentally measured focal spot sizes are comparable to that of a typical commercial mammography tube without motion blurring. Trade-off between the system spatial resolution, x-ray flux, and scanning time are also discussed. Projection images of a breast phantom were collected using the x-ray source array from 25 different viewing angles without motion. These preliminary results demonstrate the feasibility of the proposed s-DBT scanner. The technology has the potential to increase the resolution and reduce the imaging time for DBT. With the present design of 25 views, they demonstrated experimentally the feasibility of achieving 11 s scanning time at full detector resolution with
0.5
×
0.3
mm
source resolution without motion blur. The flexibility in configuration of the x-ray source array will also allow system designers to consider imaging geometries that are difficult to achieve with the conventional single-source rotating approach.</abstract><cop>United States</cop><pub>American Association of Physicists in Medicine</pub><pmid>19928069</pmid><doi>10.1118/1.3213520</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record> |
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subjects | biological organs biomedical imaging BIOMEDICAL RADIOGRAPHY breast imaging cancer carbon nanotube carbon nanotubes Cathodes CHEST Computed tomography Computer-Aided Design computerised tomography COMPUTERIZED TOMOGRAPHY DESIGN Digital mammography Electric currents Electrodes Equipment Design Equipment Failure Analysis field emission INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY Mammography Mammography - instrumentation Medical imaging Medical X‐ray imaging Modulation transfer functions phantoms RADIATION DETECTION Radiation Imaging Physics Radiographic Image Enhancement - instrumentation RADIOLOGY AND NUCLEAR MEDICINE Radiometry Reproducibility of Results Scattering, Radiation Sensitivity and Specificity SPATIAL RESOLUTION Tomography, X-Ray Computed - instrumentation tomosynthesis Transducers tumours Vacuum tubes X RADIATION x-ray X-RAY SOURCES X-Rays X‐ray applications X‐ray detectors X‐ray imaging |
title | Design and characterization of a spatially distributed multibeam field emission x-ray source for stationary digital breast tomosynthesis |
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