MLC quality assurance using EPID: A fitting technique with subpixel precision
Amorphous silicon based electronic portal imaging devices (EPIDs) have been shown to be a good alternative to radiographic film for routine quality assurance (QA) of multileaf collimator (MLC) positioning accuracy. In this work, we present a method of acquiring an EPID image of a traditional strip-t...
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description | Amorphous silicon based electronic portal imaging devices (EPIDs) have been shown to be a good alternative to radiographic film for routine quality assurance (QA) of multileaf collimator (MLC) positioning accuracy. In this work, we present a method of acquiring an EPID image of a traditional strip-test image using analytical fits of the interleaf and leaf abutment image signatures. After exposure, the EPID image pixel values are divided by an open field image to remove EPID response and radiation field variations. Profiles acquired in the direction orthogonal to the leaf motion exhibit small peaks caused by interleaf leakage. Gaussian profiles are fitted to the interleaf leakage peaks, the results of which are, using multiobjective optimization, used to calculate the image rotational angle with respect to the collimator axis of rotation. The relative angle is used to rotate the image to align the MLC leaf travel to the image pixel axes. The leaf abutments also present peaks that are fitted by heuristic functions, in this case modified Lorentzian functions. The parameters of the Lorentzian functions are used to parameterize the leaf gap width and positions. By imaging a set of MLC fields with varying gaps forming symmetric and asymmetric abutments, calibration curves with regard to relative peak height (RPH) versus nominal gap width are obtained. Based on this calibration data, the individual leaf positions are calculated to compare with the nominal programmed positions. The results demonstrate that the collimator rotation angle can be determined as accurate as
0.01
°
. A change in MLC gap width of
0.2
mm
leads to a change in RPH of about 10%. For asymmetrically produced gaps, a
0.2
mm
MLC leaf gap width change causes 0.2 pixel peak position change. Subpixel resolution is obtained by using a parameterized fit of the relatively large abutment peaks. By contrast, for symmetrical gap changes, the peak position remains unchanged with a standard deviation of 0.05 pixels, or
0.026
mm
. A trial run of 36 test images, each with gap widths varying from 0.4 to
1.4
mm
, were used to analyze 8640 abutments. The leaf position variations were detected with a precision of
0.1
mm
at a 95% confidence level, with a mean of
0.04
mm
and a standard deviation of
0.03
mm
. The proposed method is robust and minimizes the effect of image noise and pixel size and may help physicists to establish reliable and reasonable action levels in routine MLC QA. |
doi_str_mv | 10.1118/1.2919560 |
format | Article |
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0.01
°
. A change in MLC gap width of
0.2
mm
leads to a change in RPH of about 10%. For asymmetrically produced gaps, a
0.2
mm
MLC leaf gap width change causes 0.2 pixel peak position change. Subpixel resolution is obtained by using a parameterized fit of the relatively large abutment peaks. By contrast, for symmetrical gap changes, the peak position remains unchanged with a standard deviation of 0.05 pixels, or
0.026
mm
. A trial run of 36 test images, each with gap widths varying from 0.4 to
1.4
mm
, were used to analyze 8640 abutments. The leaf position variations were detected with a precision of
0.1
mm
at a 95% confidence level, with a mean of
0.04
mm
and a standard deviation of
0.03
mm
. The proposed method is robust and minimizes the effect of image noise and pixel size and may help physicists to establish reliable and reasonable action levels in routine MLC QA.</description><identifier>ISSN: 0094-2405</identifier><identifier>EISSN: 2473-4209</identifier><identifier>DOI: 10.1118/1.2919560</identifier><identifier>PMID: 18649468</identifier><identifier>CODEN: MPHYA6</identifier><language>eng</language><publisher>United States: American Association of Physicists in Medicine</publisher><subject>ACCURACY ; Amorphous semiconductors ; biomedical imaging ; CALIBRATION ; CALIBRATION STANDARDS ; COLLIMATORS ; Diagnostic Imaging - methods ; Electronics, Medical - methods ; EPID ; Image analysis ; Image guided radiation therapy ; Image Processing, Computer-Assisted ; image resolution ; IMRT ; Intensity modulated radiation therapy ; Lorentzian fitting ; Medical imaging ; MLC QA ; Multileaf collimators ; Noise ; optimisation ; OPTIMIZATION ; QUALITY ASSURANCE ; Quality assurance equipment ; Quality Control ; radiation therapy ; Radiography ; RADIOLOGY AND NUCLEAR MEDICINE ; RADIOTHERAPY ; Sensitivity and Specificity ; Silicon - chemistry ; Spatial resolution ; Therapeutic applications, including brachytherapy</subject><ispartof>Medical physics (Lancaster), 2008-06, Vol.35 (6), p.2347-2355</ispartof><rights>American Association of Physicists in Medicine</rights><rights>2008 American Association of Physicists in Medicine</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4740-10e0001cd850357b011a99425eb5abf7044dc45c2807f70ea7c4f17bfcab737b3</citedby><cites>FETCH-LOGICAL-c4740-10e0001cd850357b011a99425eb5abf7044dc45c2807f70ea7c4f17bfcab737b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1118%2F1.2919560$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1118%2F1.2919560$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>230,314,776,780,881,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18649468$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/21120754$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Mamalui-Hunter, Maria</creatorcontrib><creatorcontrib>Li, Harold</creatorcontrib><creatorcontrib>Low, Daniel A.</creatorcontrib><title>MLC quality assurance using EPID: A fitting technique with subpixel precision</title><title>Medical physics (Lancaster)</title><addtitle>Med Phys</addtitle><description>Amorphous silicon based electronic portal imaging devices (EPIDs) have been shown to be a good alternative to radiographic film for routine quality assurance (QA) of multileaf collimator (MLC) positioning accuracy. In this work, we present a method of acquiring an EPID image of a traditional strip-test image using analytical fits of the interleaf and leaf abutment image signatures. After exposure, the EPID image pixel values are divided by an open field image to remove EPID response and radiation field variations. Profiles acquired in the direction orthogonal to the leaf motion exhibit small peaks caused by interleaf leakage. Gaussian profiles are fitted to the interleaf leakage peaks, the results of which are, using multiobjective optimization, used to calculate the image rotational angle with respect to the collimator axis of rotation. The relative angle is used to rotate the image to align the MLC leaf travel to the image pixel axes. The leaf abutments also present peaks that are fitted by heuristic functions, in this case modified Lorentzian functions. The parameters of the Lorentzian functions are used to parameterize the leaf gap width and positions. By imaging a set of MLC fields with varying gaps forming symmetric and asymmetric abutments, calibration curves with regard to relative peak height (RPH) versus nominal gap width are obtained. Based on this calibration data, the individual leaf positions are calculated to compare with the nominal programmed positions. The results demonstrate that the collimator rotation angle can be determined as accurate as
0.01
°
. A change in MLC gap width of
0.2
mm
leads to a change in RPH of about 10%. For asymmetrically produced gaps, a
0.2
mm
MLC leaf gap width change causes 0.2 pixel peak position change. Subpixel resolution is obtained by using a parameterized fit of the relatively large abutment peaks. By contrast, for symmetrical gap changes, the peak position remains unchanged with a standard deviation of 0.05 pixels, or
0.026
mm
. A trial run of 36 test images, each with gap widths varying from 0.4 to
1.4
mm
, were used to analyze 8640 abutments. The leaf position variations were detected with a precision of
0.1
mm
at a 95% confidence level, with a mean of
0.04
mm
and a standard deviation of
0.03
mm
. The proposed method is robust and minimizes the effect of image noise and pixel size and may help physicists to establish reliable and reasonable action levels in routine MLC QA.</description><subject>ACCURACY</subject><subject>Amorphous semiconductors</subject><subject>biomedical imaging</subject><subject>CALIBRATION</subject><subject>CALIBRATION STANDARDS</subject><subject>COLLIMATORS</subject><subject>Diagnostic Imaging - methods</subject><subject>Electronics, Medical - methods</subject><subject>EPID</subject><subject>Image analysis</subject><subject>Image guided radiation therapy</subject><subject>Image Processing, Computer-Assisted</subject><subject>image resolution</subject><subject>IMRT</subject><subject>Intensity modulated radiation therapy</subject><subject>Lorentzian fitting</subject><subject>Medical imaging</subject><subject>MLC QA</subject><subject>Multileaf collimators</subject><subject>Noise</subject><subject>optimisation</subject><subject>OPTIMIZATION</subject><subject>QUALITY ASSURANCE</subject><subject>Quality assurance equipment</subject><subject>Quality Control</subject><subject>radiation therapy</subject><subject>Radiography</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>RADIOTHERAPY</subject><subject>Sensitivity and Specificity</subject><subject>Silicon - chemistry</subject><subject>Spatial resolution</subject><subject>Therapeutic applications, including brachytherapy</subject><issn>0094-2405</issn><issn>2473-4209</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU1LxDAURYMoOn4s_AMSEASF6kubNI0LQcZPmEEXug5pJtVIp61Nqs6_N0MrulFchQfnHW7uQ2iXwDEhJDshx7EggqWwgkYx5UlEYxCraAQgaBRTYBto07kXAEgTButog2QpFTTNRmg6nYzxa6dK6xdYOde1qtIGd85WT_jy_vbiFJ_jwnq_nL3Rz5V97Qx-t_4Zuy5v7IcpcdMabZ2tq220VqjSmZ3h3UKPV5cP45tocnd9Oz6fRJpyChEBE7IQPcsYJIznQIgSgsbM5EzlBQdKZ5oyHWfAw2QU17QgPC-0ynnC82QL7ffe2nkrnbbLZLquKqO9jAmJgTMaqIOeato6hHZezq3TpixVZerOyVQkSQYiDeBhD-q2dq41hWxaO1ftQhKQy4YlkUPDgd0bpF0-N7Nvcqg0AFEPvNvSLH43yen9IDzr-eU3lA8t_r4TjiWHY8mvYwXB0b8Ff8FvdfsjXTMrkk_hgbNE</recordid><startdate>200806</startdate><enddate>200806</enddate><creator>Mamalui-Hunter, Maria</creator><creator>Li, Harold</creator><creator>Low, Daniel A.</creator><general>American Association of Physicists in Medicine</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>OTOTI</scope></search><sort><creationdate>200806</creationdate><title>MLC quality assurance using EPID: A fitting technique with subpixel precision</title><author>Mamalui-Hunter, Maria ; Li, Harold ; Low, Daniel A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4740-10e0001cd850357b011a99425eb5abf7044dc45c2807f70ea7c4f17bfcab737b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>ACCURACY</topic><topic>Amorphous semiconductors</topic><topic>biomedical imaging</topic><topic>CALIBRATION</topic><topic>CALIBRATION STANDARDS</topic><topic>COLLIMATORS</topic><topic>Diagnostic Imaging - methods</topic><topic>Electronics, Medical - methods</topic><topic>EPID</topic><topic>Image analysis</topic><topic>Image guided radiation therapy</topic><topic>Image Processing, Computer-Assisted</topic><topic>image resolution</topic><topic>IMRT</topic><topic>Intensity modulated radiation therapy</topic><topic>Lorentzian fitting</topic><topic>Medical imaging</topic><topic>MLC QA</topic><topic>Multileaf collimators</topic><topic>Noise</topic><topic>optimisation</topic><topic>OPTIMIZATION</topic><topic>QUALITY ASSURANCE</topic><topic>Quality assurance equipment</topic><topic>Quality Control</topic><topic>radiation therapy</topic><topic>Radiography</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>RADIOTHERAPY</topic><topic>Sensitivity and Specificity</topic><topic>Silicon - chemistry</topic><topic>Spatial resolution</topic><topic>Therapeutic applications, including brachytherapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mamalui-Hunter, Maria</creatorcontrib><creatorcontrib>Li, Harold</creatorcontrib><creatorcontrib>Low, Daniel A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>OSTI.GOV</collection><jtitle>Medical physics (Lancaster)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mamalui-Hunter, Maria</au><au>Li, Harold</au><au>Low, Daniel A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>MLC quality assurance using EPID: A fitting technique with subpixel precision</atitle><jtitle>Medical physics (Lancaster)</jtitle><addtitle>Med Phys</addtitle><date>2008-06</date><risdate>2008</risdate><volume>35</volume><issue>6</issue><spage>2347</spage><epage>2355</epage><pages>2347-2355</pages><issn>0094-2405</issn><eissn>2473-4209</eissn><coden>MPHYA6</coden><abstract>Amorphous silicon based electronic portal imaging devices (EPIDs) have been shown to be a good alternative to radiographic film for routine quality assurance (QA) of multileaf collimator (MLC) positioning accuracy. In this work, we present a method of acquiring an EPID image of a traditional strip-test image using analytical fits of the interleaf and leaf abutment image signatures. After exposure, the EPID image pixel values are divided by an open field image to remove EPID response and radiation field variations. Profiles acquired in the direction orthogonal to the leaf motion exhibit small peaks caused by interleaf leakage. Gaussian profiles are fitted to the interleaf leakage peaks, the results of which are, using multiobjective optimization, used to calculate the image rotational angle with respect to the collimator axis of rotation. The relative angle is used to rotate the image to align the MLC leaf travel to the image pixel axes. The leaf abutments also present peaks that are fitted by heuristic functions, in this case modified Lorentzian functions. The parameters of the Lorentzian functions are used to parameterize the leaf gap width and positions. By imaging a set of MLC fields with varying gaps forming symmetric and asymmetric abutments, calibration curves with regard to relative peak height (RPH) versus nominal gap width are obtained. Based on this calibration data, the individual leaf positions are calculated to compare with the nominal programmed positions. The results demonstrate that the collimator rotation angle can be determined as accurate as
0.01
°
. A change in MLC gap width of
0.2
mm
leads to a change in RPH of about 10%. For asymmetrically produced gaps, a
0.2
mm
MLC leaf gap width change causes 0.2 pixel peak position change. Subpixel resolution is obtained by using a parameterized fit of the relatively large abutment peaks. By contrast, for symmetrical gap changes, the peak position remains unchanged with a standard deviation of 0.05 pixels, or
0.026
mm
. A trial run of 36 test images, each with gap widths varying from 0.4 to
1.4
mm
, were used to analyze 8640 abutments. The leaf position variations were detected with a precision of
0.1
mm
at a 95% confidence level, with a mean of
0.04
mm
and a standard deviation of
0.03
mm
. The proposed method is robust and minimizes the effect of image noise and pixel size and may help physicists to establish reliable and reasonable action levels in routine MLC QA.</abstract><cop>United States</cop><pub>American Association of Physicists in Medicine</pub><pmid>18649468</pmid><doi>10.1118/1.2919560</doi><tpages>9</tpages></addata></record> |
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source | MEDLINE; Wiley Online Library Journals Frontfile Complete; Alma/SFX Local Collection |
subjects | ACCURACY Amorphous semiconductors biomedical imaging CALIBRATION CALIBRATION STANDARDS COLLIMATORS Diagnostic Imaging - methods Electronics, Medical - methods EPID Image analysis Image guided radiation therapy Image Processing, Computer-Assisted image resolution IMRT Intensity modulated radiation therapy Lorentzian fitting Medical imaging MLC QA Multileaf collimators Noise optimisation OPTIMIZATION QUALITY ASSURANCE Quality assurance equipment Quality Control radiation therapy Radiography RADIOLOGY AND NUCLEAR MEDICINE RADIOTHERAPY Sensitivity and Specificity Silicon - chemistry Spatial resolution Therapeutic applications, including brachytherapy |
title | MLC quality assurance using EPID: A fitting technique with subpixel precision |
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