Detection of glutamate in the eye by Raman spectroscopy

Raman spectroscopy is used to detect glutamate in the eye. Glutamate, a by-product of nerve cell death, is an indicator of glaucoma and diabetic retinopathy. The Raman spectra of whole porcine eyes and individual components (lens, cornea, vitreous) are measured and characterized. Monosodium glutamat...

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Veröffentlicht in:	Journal of Biomedical Optics 2003-04, Vol.8 (2), p.167-172
Hauptverfasser:	Katz, Al, Kruger, Erik F, Minko, Glenn, Liu, C. H, Rosen, Richard B, Alfano, Robert R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cornea - chemistry Cornea - drug effects Cornea - metabolism diabetic retinopathy Diabetic Retinopathy - chemically induced Diabetic Retinopathy - metabolism Eye - chemistry Eye - drug effects Eye - metabolism glaucoma Glaucoma - chemically induced Glaucoma - metabolism glutamate In Vitro Techniques Lens, Crystalline - chemistry Lens, Crystalline - drug effects Lens, Crystalline - metabolism Raman spectroscopy Sodium Glutamate - administration & dosage Sodium Glutamate - analysis Sodium Glutamate - chemistry Sodium Glutamate - metabolism Spectrum Analysis, Raman - instrumentation Spectrum Analysis, Raman - methods Swine Tissue Distribution Vitreous Body - chemistry Vitreous Body - drug effects Vitreous Body - metabolism
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