Luminal capsaicin inhibits fluid secretion induced by enterotoxin E. coli STa, but not by carbachol, in vivo in rat small and large intestine

The enterotoxin E. coli STa induced fluid secretion in the rat jejunum, ileum and proximal colon in vivo that was greatly inhibited by the co-presence of luminal capsaicin, which is a specific neural toxin of afferent C fibres. The same dose of capsaicin had no effect on the fluid secretion activate...

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Veröffentlicht in:	Experimental physiology 1996-03, Vol.81 (2), p.313-315
Hauptverfasser:	Nzegwu, HC, Levin, RJ
Format:	Artikel
Sprache:	eng
Schlagworte:	Afferent Pathways - physiology Animals Capsaicin - pharmacology Carbachol - pharmacology Chlorides - metabolism Enterotoxins - antagonists & inhibitors Enterotoxins - pharmacology Escherichia coli Intestinal Secretions - drug effects Intestinal Secretions - physiology Nerve Fibers - drug effects Nerve Fibers - metabolism Neurotoxins - pharmacology Rats Rats, Inbred Strains
Online-Zugang:	Volltext
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