The presence of NHE1 and NHE3 Na+-H+ exchangers and an apical cAMP-independent Cl- channel indicate that both absorptive and secretory functions are present in calf gall bladder epithelium

We investigated the transport systems that can sustain Na+ and Cl- movements across bovine gall bladder epithelium, focusing on the Na+-H+ exchanger (NHE) family and chloride conductive pathways. Experiments conducted using the fluorescent probe acridine orange (AO) with brush-border membrane vesicl...

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Veröffentlicht in:	Experimental physiology 2001-09, Vol.86 (5), p.571-583
Hauptverfasser:	Bazzini, Claudia, Bottà, Guido, Meyer, Giuliano, Baroni, Maurizio David, Paulmichl, Markus
Format:	Artikel
Sprache:	eng
Schlagworte:	4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid - pharmacology Acridine Orange - metabolism Amiloride - pharmacology Amino Acid Sequence Animals Anion Transport Proteins Antiporters Biological Transport - physiology Cattle Cell Fractionation Cell Membrane - metabolism Cell Polarity Cells, Cultured Chloride Channels - metabolism Cyclic AMP - metabolism Cyclic AMP - pharmacology Cystic Fibrosis Transmembrane Conductance Regulator - chemistry Cystic Fibrosis Transmembrane Conductance Regulator - genetics Cystic Fibrosis Transmembrane Conductance Regulator - metabolism Diuretics - pharmacology Dose-Response Relationship, Drug Enzyme Inhibitors - pharmacology Epithelial Cells - cytology Epithelial Cells - drug effects Epithelial Cells - metabolism Fluorescent Dyes - metabolism Full Length Papers Gallbladder - metabolism Humans Hydrogen - metabolism Male Membrane Proteins - chemistry Membrane Proteins - genetics Membrane Proteins - metabolism Microvilli - metabolism Molecular Sequence Data Patch-Clamp Techniques Protein Isoforms Sequence Alignment SLC4A Proteins Sodium - metabolism Sodium-Hydrogen Exchanger 3 Sodium-Hydrogen Exchangers - antagonists & inhibitors Sodium-Hydrogen Exchangers - chemistry Sodium-Hydrogen Exchangers - genetics Sodium-Hydrogen Exchangers - metabolism Zinc - pharmacology
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