Effective detection of BRAF V595E mutation in canine urothelial and prostate carcinomas using immunohistochemistry

Canine urothelial carcinoma (UC) and prostate carcinoma (PC) frequently exhibit the BRAF mutation, akin to the BRAF mutation common in various human cancers. Since the initial discovery of the BRAF mutation in canine cancers in 2015, PCR has been the standard method for its detection in both liquid...

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Veröffentlicht in:	Veterinary & comparative oncology 2024-06, Vol.22 (2), p.295-302
Hauptverfasser:	Aeschlimann, Leonore, Kehl, Alexandra, Guscetti, Franco, Posthaus, Caroline, Aupperle-Lellbach, Heike, Rottenberg, Sven, de Brot, Simone
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carcinoma - diagnosis Carcinoma - genetics Carcinoma - metabolism Carcinoma - pathology Carcinoma - veterinary Carcinoma, Transitional Cell - diagnosis Carcinoma, Transitional Cell - genetics Carcinoma, Transitional Cell - metabolism Carcinoma, Transitional Cell - pathology Carcinoma, Transitional Cell - veterinary Dog Diseases - diagnosis Dog Diseases - genetics Dog Diseases - pathology Dogs Female Immunohistochemistry - veterinary Male Mutation Prostatic Neoplasms - diagnosis Prostatic Neoplasms - genetics Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology Prostatic Neoplasms - veterinary Proto-Oncogene Proteins B-raf - genetics Urinary Bladder Neoplasms - diagnosis Urinary Bladder Neoplasms - genetics Urinary Bladder Neoplasms - metabolism Urinary Bladder Neoplasms - pathology Urinary Bladder Neoplasms - veterinary
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