Cell cycle kinetics, apoptosis rates and gene expressions of MDR‐1, TP53, BCL‐2 and BAX in transmissible venereal tumour cells and their association with therapy response

Transmissible venereal tumour (TVT) generally presents different degrees of aggressiveness, which makes them unresponsive to conventional treatment protocols. This implies a progressive alteration of their biological profile. This study aimed to evaluate the cytotoxicity, cell survival, apoptosis an...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Veterinary & comparative oncology 2017-09, Vol.15 (3), p.793-807
Hauptverfasser:	Flórez, M. M., Fêo, H. B., da Silva, G. N., Yamatogi, R. S., Aguiar, A. J., Araújo, J. P., Rocha, N. S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents, Phytogenic - therapeutic use apoptosis Apoptosis - drug effects ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism bcl-2-Associated X Protein - metabolism Cell Cycle - drug effects Cell Line, Tumor chemotherapy cytotoxicity Dog Diseases - drug therapy Dog Diseases - pathology Dogs Dose-Response Relationship, Drug Gene Expression Regulation, Neoplastic MDR‐1 Proto-Oncogene Proteins c-bcl-2 - metabolism toxicogenomic Treatment Outcome Tumor Suppressor Protein p53 - metabolism Venereal Tumors, Veterinary - drug therapy Venereal Tumors, Veterinary - pathology Vincristine - therapeutic use
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!