Clinical efficiency and safety of Hsp90 inhibitor Novobiocin in avian tibial dyschondroplasia

Tibial dyschondroplasia (TD) is a bone defect of broilers and other poultry birds that disturbs growth plate and it causes lameness. Previously we evaluated differential expression of multiple genes involved in growth plate angiogenesis and reported the safety and efficacious of medicinal plant root...

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Veröffentlicht in:	Journal of veterinary pharmacology and therapeutics 2018-12, Vol.41 (6), p.902-911
Hauptverfasser:	Nabi, Fazul, Iqbal, Muhammad K., Zhang, Hui, Rehman, Mujeeb Ur, Shahzad, Muhammad, Huang, Shucheng, Han, Zhaoqing, Mehmood, Khalid, Ahmed, Nisar, Chachar, Bahram, Arain, Muhammad A., Li, Jiakui
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals bone broiler Chickens Enzyme Inhibitors - therapeutic use Gene Expression Regulation - drug effects Growth Plate - drug effects Hsp90 HSP90 Heat-Shock Proteins - antagonists & inhibitors novobiocin Novobiocin - therapeutic use Osteochondrodysplasias - chemically induced Osteochondrodysplasias - drug therapy Osteochondrodysplasias - veterinary Poultry Diseases - drug therapy Thiram - adverse effects Tibia - drug effects tibial dyschondroplasia toxicity
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