Human endothelial cells size‐select their secretory granules for exocytosis to modulate their functional output

Background The secretory granules of endothelial cells, Weibel‐Palade bodies, are released in response to numerous extracellular signals. Their cargo is critical to many vascular functions including hemostasis and inflammation. This presents a fundamental problem: how can these cells initiate tailor...

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Veröffentlicht in:Journal of thrombosis and haemostasis 2020-01, Vol.18 (1), p.243-254
Hauptverfasser: McCormack, Jessica J., Harrison‐Lavoie, Kimberly J., Cutler, Daniel F.
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Sprache:eng
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