Resveratrol Stimulates Hydrogen Sulfide (H2S) Formation to Relax Murine Corpus Cavernosum

Resveratrol (RVT) found in red wine protects against erectile dysfunction and relaxes penile tissue (corpus cavernosum) via a nitric oxide (NO) independent pathway. However, the mechanism remains to be elucidated. Hydrogen sulfide (H2S) is a potent vasodilator and neuromodulator generated in corpus...

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Veröffentlicht in:	Journal of sexual medicine 2015-10, Vol.12 (10), p.2004-2012
Hauptverfasser:	Yetik-Anacak, Gunay, Dereli, Mehmet V., Sevin, Gulnur, Ozzayım, Ozge, Erac, Yasemin, Ahmed, Asif
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arginine - pharmacology Corpus Cavernosum Cysteine - metabolism Cysteine - physiology Erectile Dysfunction Hydrogen Sulfide Hydrogen Sulfide - metabolism Male Mice Muscle Relaxation - drug effects Nitric Oxide - metabolism Penile Erection - drug effects Penis - drug effects Penis - pathology Phosphodiesterase 5 Inhibitor Resveratrol Signal Transduction - drug effects Stilbenes - pharmacology Vasodilator Agents - pharmacology
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