Melatonin protects against thoracic aortic aneurysm and dissection through SIRT1‐dependent regulation of oxidative stress and vascular smooth muscle cell loss

Melatonin functions as an endogenous protective molecule in multiple vascular diseases, whereas its effects on thoracic aortic aneurysm and dissection (TAAD) and underlying mechanisms have not been reported. In this study, TAAD mouse model was successfully induced by β‐aminopropionitrile fumarate (B...

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Veröffentlicht in:	Journal of pineal research 2020-08, Vol.69 (1), p.e12661-n/a
Hauptverfasser:	Xia, Lin, Sun, Chang, Zhu, Hanzhao, Zhai, Mengen, Zhang, Liyun, Jiang, Liqing, Hou, Peng, Li, Junfeng, Li, Kaifeng, Liu, Zhenhua, Li, Buying, Wang, Xiaowu, Yi, Wei, Liang, Hongliang, Jin, Zhenxiao, Yang, Jian, Yi, Dinghua, Liu, Jincheng, Yu, Shiqiang, Duan, Weixun
Format:	Artikel
Sprache:	eng
Schlagworte:	melatonin melatonin receptor oxidative stress sirtuin‐1 thoracic aortic aneurysm and dissection vascular smooth muscle cell
Online-Zugang:	Volltext
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