Hypothermic circulatory arrest for aortic dissection with cryoglobulinemia

Cryoglobulinemia is a cold‐reactive autoimmune disease. A 64‐year‐old man with active cryoglobulinemia presented Stanford type A acute aortic dissection. He had been treated with immunosuppressive drugs and plasma exchange (PE) at our hospital; subsequently, qualitative analysis of cryoglobulin (CG)...

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Veröffentlicht in:Journal of cardiac surgery 2020-11, Vol.35 (11), p.3169-3172
Hauptverfasser: Yamazaki, Kazuhiro, Minatoya, Kenji, Sakamoto, Kazuhisa, Kitagori, Koji, Okuda, Masanori, Murakami, Kosaku
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container_end_page 3172
container_issue 11
container_start_page 3169
container_title Journal of cardiac surgery
container_volume 35
creator Yamazaki, Kazuhiro
Minatoya, Kenji
Sakamoto, Kazuhisa
Kitagori, Koji
Okuda, Masanori
Murakami, Kosaku
description Cryoglobulinemia is a cold‐reactive autoimmune disease. A 64‐year‐old man with active cryoglobulinemia presented Stanford type A acute aortic dissection. He had been treated with immunosuppressive drugs and plasma exchange (PE) at our hospital; subsequently, qualitative analysis of cryoglobulin (CG) was negative. He underwent emergency ascending aorta replacement using cardiopulmonary bypass (CPB) under deep hypothermia circulatory arrest with selective cerebral perfusion. The total CPB time, aortic cross‐clamp time, and selective cerebral perfusion time were 255, 153, 56 minutes, respectively, and the minimal nasopharyngeal temperature was 17.3°C. Our patient had no significant perioperative complications. Hence, if PE is performed appropriately and CG is negative, patients with cryoglobulinemia who exhibit severe preoperative symptoms can safely undergo surgery with deep hypothermia.
doi_str_mv 10.1111/jocs.14908
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A 64‐year‐old man with active cryoglobulinemia presented Stanford type A acute aortic dissection. He had been treated with immunosuppressive drugs and plasma exchange (PE) at our hospital; subsequently, qualitative analysis of cryoglobulin (CG) was negative. He underwent emergency ascending aorta replacement using cardiopulmonary bypass (CPB) under deep hypothermia circulatory arrest with selective cerebral perfusion. The total CPB time, aortic cross‐clamp time, and selective cerebral perfusion time were 255, 153, 56 minutes, respectively, and the minimal nasopharyngeal temperature was 17.3°C. Our patient had no significant perioperative complications. 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subjects Aneurysm, Dissecting - complications
Aneurysm, Dissecting - surgery
Aorta - surgery
Blood Vessel Prosthesis Implantation - methods
Cardiopulmonary Bypass
Circulatory Arrest, Deep Hypothermia Induced - methods
cryoglobulin
cryoglobulinemia
Cryoglobulinemia - complications
Cryoglobulinemia - embryology
Cryoglobulinemia - therapy
deep hypothermia
Humans
Immunosuppressive Agents - therapeutic use
Male
Middle Aged
Plasma Exchange
Postoperative Complications - prevention & control
Treatment Outcome
title Hypothermic circulatory arrest for aortic dissection with cryoglobulinemia
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