Serum diamine oxidase activity as a predictor of gastrointestinal toxicity and malnutrition due to anticancer drugs

Background and Aim Objective evaluation of intestinal mucosal damage due to anticancer drugs is generally difficult. Serum diamine oxidase (DAO) activity is reported to reflect the integrity and maturity of the small intestinal mucosa. Therefore, we investigated whether serum DAO activity is an indi...

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Veröffentlicht in:	Journal of gastroenterology and hepatology 2015-11, Vol.30 (11), p.1582-1590
Hauptverfasser:	Miyoshi, Jinsei, Miyamoto, Hiroshi, Goji, Takahiro, Taniguchi, Tatsuya, Tomonari, Tetsu, Sogabe, Masahiro, Kimura, Tetsuo, Kitamura, Shinji, Okamoto, Koichi, Fujino, Yasuteru, Muguruma, Naoki, Okahisa, Toshiya, Takayama, Tetsuji
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Amine Oxidase (Copper-Containing) - blood anticancer drugs Antineoplastic Agents - adverse effects Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biomarkers - blood Cisplatin - administration & dosage Cisplatin - adverse effects diamine oxidase diarrhea Drug Combinations Duodenum - drug effects Female Gastrointestinal Diseases - chemically induced Gastrointestinal Diseases - diagnosis gastrointestinal toxicity Humans Intestinal Mucosa - drug effects Male malnutrition Malnutrition - chemically induced Malnutrition - diagnosis Middle Aged Oxonic Acid - administration & dosage Oxonic Acid - adverse effects Prospective Studies Sensitivity and Specificity Stomach Neoplasms - drug therapy Stomach Neoplasms - secondary Taxoids - administration & dosage Taxoids - adverse effects Tegafur - administration & dosage Tegafur - adverse effects
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