M2 polarization of tumor‐associated macrophages is dependent on integrin β 3 via peroxisome proliferator‐activated receptor‐ γ up‐regulation in breast cancer

Macrophages are particularly abundant and play an important role throughout the tumor progression process, namely, tumor‐associated macrophages (TAM) in the tumor microenvironment. TAM can be polarized to disparate functional phenotypes, the M1 and M2 macrophages. M1‐like type macrophages are define...

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Veröffentlicht in:Immunology 2020-08, Vol.160 (4), p.345-356
Hauptverfasser: Shu, Yuxin, Qin, Menghao, Song, Yue, Tang, Qing, Huang, Yahong, Shen, Pingping, Lu, Yan
Format: Artikel
Sprache:eng
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