Soluble CD 14 is essential for lipopolysaccharide‐dependent activation of human intestinal mast cells from macroscopically normal as well as C rohn's disease tissue

Mast cells are now considered sentinels in immunity. Given their location underneath the gastrointestinal barrier, mast cells are entrusted with the task of tolerating commensal microorganisms and eliminating potential pathogens in the gut microbiota. The aim of our study was to analyse the responsi...

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Veröffentlicht in:Immunology 2014-10, Vol.143 (2), p.174-183
Hauptverfasser: Brenner, Sibylle A., Zacheja, Steffi, Schäffer, Michael, Feilhauer, Katharina, Bischoff, Stephan C., Lorentz, Axel
Format: Artikel
Sprache:eng
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