Successful achievement of sustained virological response to triple combination therapy containing simeprevir in two patients with chronic hepatitis C who had failed asunaprevir:Daclatasvir combination therapy

Patients 1 and 2 were treatment‐naive women who had genotype 1b chronic hepatitis C. Both had IL‐28B genotype TT, and amino acid substitutions of core 70 and 91 were both wild type. Search for the presence of resistance‐associated variants (RAV) in non‐structural (NS)3 and NS5A regions confirmed wil...

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Veröffentlicht in:	Hepatology research 2016-10, Vol.46 (11), p.1162-1167
Hauptverfasser:	Ozeki, Itaru, Nakajima, Tomoaki, Yamaguchi, Masakatsu, Kimura, Mutsuumi, Arakawa, Tomohiro, Kuwata, Yasuaki, Ohmura, Takumi, Sato, Takahiro, Hige, Shuhei, Karino, Yoshiyasu, Toyota, Joji
Format:	Artikel
Sprache:	eng
Schlagworte:	asunaprevir daclatasvir hepatitis C virus interferon resistance‐associated variants
Online-Zugang:	Volltext
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