Methotrexate induced pneumatosis intestinalis under hemodialysis patient
Pneumatosis intestinalis (PI) is a rare disorder characterized by the gas within the intestinal mucosa. This is the first report methotrexate (MTX) induced PI under hemodialysis (HD) patient. A 46‐year‐old man suffered rheumatoid arthritis and underwent HD at local HD center. After the initial induc...
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| Veröffentlicht in: | Hemodialysis international 2017-01, Vol.21 (1), p.E9-E12 |
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| creator | Mima, Akira Nagahara, Dai Tansho, Kosuke |
| description | Pneumatosis intestinalis (PI) is a rare disorder characterized by the gas within the intestinal mucosa. This is the first report methotrexate (MTX) induced PI under hemodialysis (HD) patient. A 46‐year‐old man suffered rheumatoid arthritis and underwent HD at local HD center. After the initial induction of MTX, the patient showed epigastralgia and diarrhea. He was referred to our hospital and abdominal computed tomography showed significant large intestinal edema and free intraperitoneal air consistent with PI. Physicians should aware that MTX is contraindication drug for chronic kidney disease and high‐flux HD may decrease MTX toxicity and oxidative stress, improving PI. |
| doi_str_mv | 10.1111/hdi.12459 |
| format | Article |
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This is the first report methotrexate (MTX) induced PI under hemodialysis (HD) patient. A 46‐year‐old man suffered rheumatoid arthritis and underwent HD at local HD center. After the initial induction of MTX, the patient showed epigastralgia and diarrhea. He was referred to our hospital and abdominal computed tomography showed significant large intestinal edema and free intraperitoneal air consistent with PI. Physicians should aware that MTX is contraindication drug for chronic kidney disease and high‐flux HD may decrease MTX toxicity and oxidative stress, improving PI.</description><identifier>ISSN: 1492-7535</identifier><identifier>EISSN: 1542-4758</identifier><identifier>DOI: 10.1111/hdi.12459</identifier><identifier>PMID: 27381347</identifier><language>eng</language><publisher>Canada</publisher><subject>Antirheumatic Agents - adverse effects ; chronic kidney disease (CKD) ; hemodialysis (HD) ; Humans ; Male ; methotrexate (MTX) ; Methotrexate - adverse effects ; Middle Aged ; Pneumatosis Cystoides Intestinalis - chemically induced ; Pneumatosis intestinalis (PI) ; Renal Dialysis - adverse effects</subject><ispartof>Hemodialysis international, 2017-01, Vol.21 (1), p.E9-E12</ispartof><rights>2016 International Society for Hemodialysis</rights><rights>2016 International Society for Hemodialysis.</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3589-2c18536739a69a9d2c1941363cb6542e407ee94060997739b2ccfa4cd13325a3</citedby><cites>FETCH-LOGICAL-c3589-2c18536739a69a9d2c1941363cb6542e407ee94060997739b2ccfa4cd13325a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fhdi.12459$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fhdi.12459$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>315,781,785,1418,27929,27930,45579,45580</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27381347$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mima, Akira</creatorcontrib><creatorcontrib>Nagahara, Dai</creatorcontrib><creatorcontrib>Tansho, Kosuke</creatorcontrib><title>Methotrexate induced pneumatosis intestinalis under hemodialysis patient</title><title>Hemodialysis international</title><addtitle>Hemodial Int</addtitle><description>Pneumatosis intestinalis (PI) is a rare disorder characterized by the gas within the intestinal mucosa. This is the first report methotrexate (MTX) induced PI under hemodialysis (HD) patient. A 46‐year‐old man suffered rheumatoid arthritis and underwent HD at local HD center. After the initial induction of MTX, the patient showed epigastralgia and diarrhea. He was referred to our hospital and abdominal computed tomography showed significant large intestinal edema and free intraperitoneal air consistent with PI. Physicians should aware that MTX is contraindication drug for chronic kidney disease and high‐flux HD may decrease MTX toxicity and oxidative stress, improving PI.</description><subject>Antirheumatic Agents - adverse effects</subject><subject>chronic kidney disease (CKD)</subject><subject>hemodialysis (HD)</subject><subject>Humans</subject><subject>Male</subject><subject>methotrexate (MTX)</subject><subject>Methotrexate - adverse effects</subject><subject>Middle Aged</subject><subject>Pneumatosis Cystoides Intestinalis - chemically induced</subject><subject>Pneumatosis intestinalis (PI)</subject><subject>Renal Dialysis - adverse effects</subject><issn>1492-7535</issn><issn>1542-4758</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kMlOwzAQhi0EoqVw4AVQrxzSeo3jIypLKxVx6T1y7YlilE2xI8jb4xLgxlxm-_Rr5kfoluAVibEurVsRyoU6Q3MiOE24FNl5rLmiiRRMzNCV9-8YU4JxeolmVLKMMC7naPsKoWxDD586wNI1djBgl10DQ61D652PswA-uEZXsRkaC_2yhLq1Tlfjad_p4KAJ1-ii0JWHm5-8QIfnp8Nmm-zfXnabh31imMhUQg3JBEslUzpVWtnYK05YyswxjZcDxxJAcZxipWSkjtSYQnNjCWNUaLZA95Os6Vvveyjyrne17sec4PxkRh7NyL_NiOzdxHbDsQb7R_5-H4H1BHy4Csb_lfLt426S_AIK8Gk-</recordid><startdate>201701</startdate><enddate>201701</enddate><creator>Mima, Akira</creator><creator>Nagahara, Dai</creator><creator>Tansho, Kosuke</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>201701</creationdate><title>Methotrexate induced pneumatosis intestinalis under hemodialysis patient</title><author>Mima, Akira ; Nagahara, Dai ; Tansho, Kosuke</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3589-2c18536739a69a9d2c1941363cb6542e407ee94060997739b2ccfa4cd13325a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Antirheumatic Agents - adverse effects</topic><topic>chronic kidney disease (CKD)</topic><topic>hemodialysis (HD)</topic><topic>Humans</topic><topic>Male</topic><topic>methotrexate (MTX)</topic><topic>Methotrexate - adverse effects</topic><topic>Middle Aged</topic><topic>Pneumatosis Cystoides Intestinalis - chemically induced</topic><topic>Pneumatosis intestinalis (PI)</topic><topic>Renal Dialysis - adverse effects</topic><toplevel>online_resources</toplevel><creatorcontrib>Mima, Akira</creatorcontrib><creatorcontrib>Nagahara, Dai</creatorcontrib><creatorcontrib>Tansho, Kosuke</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Hemodialysis international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mima, Akira</au><au>Nagahara, Dai</au><au>Tansho, Kosuke</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Methotrexate induced pneumatosis intestinalis under hemodialysis patient</atitle><jtitle>Hemodialysis international</jtitle><addtitle>Hemodial Int</addtitle><date>2017-01</date><risdate>2017</risdate><volume>21</volume><issue>1</issue><spage>E9</spage><epage>E12</epage><pages>E9-E12</pages><issn>1492-7535</issn><eissn>1542-4758</eissn><abstract>Pneumatosis intestinalis (PI) is a rare disorder characterized by the gas within the intestinal mucosa. This is the first report methotrexate (MTX) induced PI under hemodialysis (HD) patient. A 46‐year‐old man suffered rheumatoid arthritis and underwent HD at local HD center. After the initial induction of MTX, the patient showed epigastralgia and diarrhea. He was referred to our hospital and abdominal computed tomography showed significant large intestinal edema and free intraperitoneal air consistent with PI. Physicians should aware that MTX is contraindication drug for chronic kidney disease and high‐flux HD may decrease MTX toxicity and oxidative stress, improving PI.</abstract><cop>Canada</cop><pmid>27381347</pmid><doi>10.1111/hdi.12459</doi><tpages>4</tpages></addata></record> |
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| ispartof | Hemodialysis international, 2017-01, Vol.21 (1), p.E9-E12 |
| issn | 1492-7535 1542-4758 |
| language | eng |
| recordid | cdi_crossref_primary_10_1111_hdi_12459 |
| source | MEDLINE; Access via Wiley Online Library |
| subjects | Antirheumatic Agents - adverse effects chronic kidney disease (CKD) hemodialysis (HD) Humans Male methotrexate (MTX) Methotrexate - adverse effects Middle Aged Pneumatosis Cystoides Intestinalis - chemically induced Pneumatosis intestinalis (PI) Renal Dialysis - adverse effects |
| title | Methotrexate induced pneumatosis intestinalis under hemodialysis patient |
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