CCAR 1/ C o C o A pair‐mediated recruitment of the Mediator defines a novel pathway for GATA 1 function

The MED1 subunit of the Mediator transcriptional coregulator complex coactivates GATA1 and induces erythropoiesis. Here, we show the dual mechanism of GATA1‐ and MED1‐mediated transcription. MED1 expression levels in K562 erythroleukemia cells paralleled the levels of GATA1‐targeted gene transcripti...

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Veröffentlicht in:Genes to cells : devoted to molecular & cellular mechanisms 2014-01, Vol.19 (1), p.28-51
Hauptverfasser: Mizuta, Shumpei, Minami, Tomoya, Fujita, Haruka, Kaminaga, Chihiro, Matsui, Keiji, Ishino, Ruri, Fujita, Azusa, Oda, Kasumi, Kawai, Asami, Hasegawa, Natsumi, Urahama, Norinaga, Roeder, Robert G., Ito, Mitsuhiro
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Sprache:eng
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