LOXL 2‐mediated chromatin compaction is required to maintain the oncogenic properties of triple‐negative breast cancer cells

Oxidation of histone H3 at lysine 4 (H3K4ox) is catalyzed by lysyl oxidase homolog 2 (LOXL2). This histone modification is enriched in heterochromatin in triple‐negative breast cancer (TNBC) cells and has been linked to the maintenance of compacted chromatin. However, the molecular mechanism underly...

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Veröffentlicht in:	The FEBS journal 2024-06, Vol.291 (11), p.2423-2448
Hauptverfasser:	Serra‐Bardenys, Gemma, Blanco, Enrique, Escudero‐Iriarte, Carmen, Serra‐Camprubí, Queralt, Querol, Jessica, Pascual‐Reguant, Laura, Morancho, Beatriz, Escorihuela, Marta, Tissera, Natalia Soledad, Sabé, Anna, Martín, Luna, Segura‐Bayona, Sandra, Verde, Gaetano, Aiese Cigliano, Riccardo, Millanes‐Romero, Alba, Jerónimo, Celia, Cebrià‐Costa, Joan Pau, Nuciforo, Paolo, Simonetti, Sara, Viaplana, Cristina, Dienstmann, Rodrigo, Oliveira, Mafalda, Peg, Vicente, Stracker, Travis H., Arribas, Joaquín, Canals, Francesc, Villanueva, Josep, Di Croce, Luciano, García de Herreros, Antonio, Tian, Tian V., Peiró, Sandra
Format:	Artikel
Sprache:	eng
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