Understanding the interaction of 14‐3‐3 proteins with h DMX and h DM2: a structural and biophysical study

p53 plays a critical role in regulating diverse biological processes: DNA repair, cell cycle arrest, apoptosis and senescence. The p53 pathway has therefore served as the focus of multiple drug‐discovery efforts. p53 is negatively regulated by h DMX and h DM2; prior studies have identified 14‐3‐3 pr...

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Veröffentlicht in:	The FEBS journal 2022-09, Vol.289 (17), p.5341-5358
Hauptverfasser:	Srdanović, Sonja, Wolter, Madita, Trinh, Chi H., Ottmann, Christian, Warriner, Stuart L., Wilson, Andrew J.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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