MTHFR C677T polymorphism: association with lymphoid neoplasm and effect on methotrexate therapy

The aim of this study was to detect the possible role of methylene tetrahydrofolate reductase gene polymorphism (MTHFR C677T) in the pathogenesis of lymphoid neoplasms and to investigate the influence of this polymorphism on methotrexate toxicity in adult ALL patients treated with methotrexate maint...

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Veröffentlicht in:	European journal of haematology 2014-07, Vol.93 (1), p.63-69
Hauptverfasser:	Ayad, Mona W., El Naggar, Amel A., El Naggar, Mostafa
Format:	Artikel
Sprache:	eng
Schlagworte:	acute lymphoblastic leukemia Adult Base Sequence DNA Primers Female Humans Lymphoma, Non-Hodgkin - drug therapy Lymphoma, Non-Hodgkin - genetics Male Methotrexate - therapeutic use Methylenetetrahydrofolate Reductase (NADPH2) - genetics Middle Aged MTHFR 677C>T non-Hodgkin lymphoma Polymorphism, Genetic Young Adult
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