Safety and tolerability of high‐intensity statin therapy in heart transplant patients receiving immunosuppression with tacrolimus

Background Following heart transplantation (HT), HMG CoA reductase inhibitors (statins) have been shown to reduce total and low‐density lipoprotein (LDL) cholesterol, development of cardiac allograft vasculopathy (CAV), and mortality. Studies in HT patients have demonstrated the safety of low/modera...

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Veröffentlicht in:	Clinical transplantation 2019-01, Vol.33 (1), p.e13454-n/a
Hauptverfasser:	Heeney, Stephanie A., Tjugum, Shelby L., Corkish, Morgan E., Hollis, Ian B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult atorvastatin calcium coronary artery disease Drug Therapy, Combination Female Follow-Up Studies graft rejection Heart Diseases - surgery heart transplantation Heart Transplantation - methods Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use hydroxymethylglutaryl‐CoA reductase inhibitors Hyperlipidemias - prevention & control Immunosuppressive Agents - therapeutic use Incidence Male Maximum Tolerated Dose Middle Aged Postoperative Complications - drug therapy Postoperative Complications - epidemiology Prognosis Retrospective Studies rosuvastatin calcium tacrolimus Tacrolimus - therapeutic use United States - epidemiology
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