Lin28a forms an RNA-binding complex with Igf2bp3 to regulate m 6 A-modified stress response genes in stress granules of muscle stem cells

In the early embryonic stages, Lin-28 homologue A (Lin28a) is highly expressed and declines as the embryo matures. As an RNA-binding protein, Lin28a maintains some adult muscle stem cells (MuSCs) in an embryonic-like state, but its RNA metabolism regulation mechanism remains unclear. BioGPS analysis...

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Veröffentlicht in:	Cell proliferation 2024-12, Vol.57 (12), p.e13707
Hauptverfasser:	Song, Dan, Chen, Yu, Wang, Peng, Cheng, Yeqian, Shyh-Chang, Ng
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine - analogs & derivatives Adenosine - metabolism Animals Cell Proliferation Humans Mice Muscle, Skeletal - cytology Muscle, Skeletal - metabolism RNA-Binding Proteins - genetics RNA-Binding Proteins - metabolism Stem Cells - cytology Stem Cells - metabolism Stress Granules - metabolism
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