IgE and allergen-specific immunotherapy-induced IgG 4 recognize similar epitopes of Bet v 1, the major allergen of birch pollen

Allergen-specific immunotherapy (AIT) with birch pollen generates Bet v 1-specific immunoglobulin (Ig)G which blocks IgE-mediated hypersensitivity mechanisms. Whether IgG specific for Bet v 1a competes with IgE for identical epitopes or whether novel epitope specificities of IgG antibodies are devel...

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Veröffentlicht in:	Clinical and experimental allergy 2017-05, Vol.47 (5), p.693-703
Hauptverfasser:	Groh, N, von Loetzen, C S, Subbarayal, B, Möbs, C, Vogel, L, Hoffmann, A, Fötisch, K, Koutsouridou, A, Randow, S, Völker, E, Seutter von Loetzen, A, Rösch, P, Vieths, S, Pfützner, W, Bohle, B, Schiller, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Plant - immunology Desensitization, Immunologic Epitopes - immunology Female Humans Immunoglobulin E - blood Immunoglobulin E - immunology Immunoglobulin G - blood Immunoglobulin G - immunology Male Mice Rhinitis, Allergic, Seasonal - blood Rhinitis, Allergic, Seasonal - immunology Rhinitis, Allergic, Seasonal - therapy
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