In silico and in vitro studies of a number PILs as new antibacterials against MDR clinical isolate Acinetobacter baumannii

QSAR analysis of a set of previously synthesized phosphonium ionic liquids (PILs) tested against Gram‐negative multidrug‐resistant clinical isolate Acinetobacter baumannii was done using the Online Chemical Modeling Environment (OCHEM). To overcome the problem of overfitting due to descriptor select...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Chemical biology & drug design 2020-06, Vol.95 (6), p.624-630
Hauptverfasser:	Trush, Maria M., Kovalishyn, Vasyl, Hodyna, Diana, Golovchenko, Olexandr V., Chumachenko, Svitlana, Tetko, Igor V., Brovarets, Volodymyr S., Metelytsia, Larysa
Format:	Artikel
Sprache:	eng
Schlagworte:	Acinetobacter baumanii antibacterial activity machine learning OCHEM phosphonium ionic liquids
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!