Design and synthesis of a novel peptide for selective detection of cancer cells

Using a minimalist approach, an 11‐residue peptide (Peptide 1) tagged with rhodamine fluorophore was designed and synthesized for selective detection of cancer cells. Peptide 1 contains RGD and NGR motifs to bind, respectively, integrins and aminopeptidase CD13, which are over expressed in cancer ce...

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Veröffentlicht in:	Chemical biology & drug design 2020-06, Vol.95 (6), p.610-623
Hauptverfasser:	Rajavenkatesh, Krishnamoorthy, Padmaja, Murali, Janani, Indrakumar, Aishwarya, Satish, Purna Sai, Korrapati, Thennarasu, Sathiah
Format:	Artikel
Sprache:	eng
Schlagworte:	cell‐selective binding fluorescence peptide synthesis peptide‐membrane interactions surface activity targeting cancer cells
Online-Zugang:	Volltext
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