Neutrophil β 1 adrenoceptor blockade blunts stroke-associated neuroinflammation

Reperfusion therapy is the standard of care for ischaemic stroke; however, there is a need to identify new therapeutic targets able to ameliorate cerebral damage. Neutrophil β adrenoceptors (β1AR) have been linked to neutrophil migration during exacerbated inflammation. Given the central role of neu...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	British journal of pharmacology 2023-02, Vol.180 (4), p.459-478
Hauptverfasser:	Clemente-Moragón, Agustín, Oliver, Eduardo, Calle, Daniel, Cussó, Lorena, Gómez, Mónica, Pradillo, Jesús M, Castejón, Raquel, Rallón, Norma, Benito, José M, Fernández-Ferro, José C, Carneado-Ruíz, Joaquín, Moro, María A, Sánchez-González, Javier, Fuster, Valentín, Cortés-Canteli, Marta, Desco, Manuel, Ibáñez, Borja
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain Ischemia - metabolism Ischemic Stroke - metabolism Metoprolol - metabolism Metoprolol - pharmacology Metoprolol - therapeutic use Neuroinflammatory Diseases Neutrophils - metabolism Rats Receptors, Adrenergic - metabolism Stroke - drug therapy Stroke - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!