The ABCB 1 , rs9282564, AG and TT Genotypes and the COMT , rs4680, AA Genotype are Less Frequent in Deceased Patients with Opioid Addiction than in Living Patients with Opioid Addiction

Sudden death due to acute intoxication occurs frequently in patients with opioid addiction ( OA ). To examine whether certain genotypes were associated with this, we examined the frequencies of 29 SNP s located in candidate genes related to opioid pharmacology: ABCB 1 , OPRM 1 , UGT 2B7 , CYP 3A5 ,...

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Veröffentlicht in:Basic & clinical pharmacology & toxicology 2016-10, Vol.119 (4), p.381-388
Hauptverfasser: Christoffersen, Dorte J., Damkier, Per, Feddersen, Søren, Möller, Sören, Thomsen, Jørgen L., Brasch‐Andersen, Charlotte, Brøsen, Kim
Format: Artikel
Sprache:eng
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