Clinical utiliy of a model‐based piperacillin dose in neonates with early‐onset sepsis

Aims Early‐onset sepsis (EOS) is a common disease in neonates with a high morbidity and mortality rate. Piperacillin/tazobactam has been used extensively and empirically for EOS treatment without clinically validated dosing regimens, although the population pharmacokinetics (PPK) of piperacillin in...

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Veröffentlicht in:	British journal of clinical pharmacology 2022-03, Vol.88 (3), p.1179-1188
Hauptverfasser:	Wu, Yue‐E, Hou, Shan‐Shan, Fang, Zeng‐Yu, Tang, Bo‐Hao, Yao, Bu‐Fan, Dong, Yi‐Ning, Li, Xue, Shi, Hai‐Yan, Zheng, Yi, Hao, Guo‐Xiang, Huang, Xin, Van Den Anker, John, Yu, Yong‐Hui, Zhao, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	clinical validation dosing optimization early‐onset sepsis neonates piperacillin
Online-Zugang:	Volltext
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