If there were an effective pharmacotherapy for cocaine use disorder, what would it do?
Although 30 years of research into an effective cocaine pharmacotherapy has yielded no treatments, knowledge gained doing this work underscores the importance of rigorous clinical design, of attention to medication adherence and of defining endpoints. The field needs a high‐risk/high‐reward strategy...
Gespeichert in:
| Veröffentlicht in: | Addiction (Abingdon, England) England), 2021-04, Vol.116 (4), p.714-715 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 715 |
|---|---|
| container_issue | 4 |
| container_start_page | 714 |
| container_title | Addiction (Abingdon, England) |
| container_volume | 116 |
| creator | Shoptaw, Steven Trivedi, Madhukar Potter, Jennifer S. |
| description | Although 30 years of research into an effective cocaine pharmacotherapy has yielded no treatments, knowledge gained doing this work underscores the importance of rigorous clinical design, of attention to medication adherence and of defining endpoints. The field needs a high‐risk/high‐reward strategy to engineer new compounds that help people to use less cocaine and to preserve gains made during treatment, particularly during lapse/relapse. |
| doi_str_mv | 10.1111/add.15310 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_crossref_primary_10_1111_add_15310</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2509232066</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4430-142ae274ca69e0fca94bf3e1d3e3f77d7c6d15e616c1ca5b5f1560d9f8aadf893</originalsourceid><addsrcrecordid>eNqNkV1rFDEUhoModq1e-Ack4I2i0yaTr8mNUrZ-FAreqLchm5y4KbOTNZnpsv--2e66qCCYi-TAec7hCS9Czyk5o_WcW-_PqGCUPEAzyiRpCOfsIZoRLUXTUk5O0JNSbgghqtP8MTphrJWaq26Gvl8FPC4hA97sLjtgCAHcGG8Br5c2r6xLu75db3FIGbvkbBwATwWwjyVlD_kt3iztiDdp6j2OI_bp_VP0KNi-wLPDe4q-ffzwdf65uf7y6Wp-cd24akgaylsLreLOSg0kOKv5IjCgngELSnnlpKcCJJWOOisWIlAhidehs9aHTrNT9G6_dz0tVuAdDGO2vVnnuLJ5a5KN5s_OEJfmR7o1HaG0a0ld8OqwIKefE5TRrGJx0Pd2gDQV03IplWJc04q-_Au9SVMe6vdMK4huWUukrNTrPeVyKiVDOMpQYnZpmZqWuU-rsi9-tz-Sv-KpwJs9sIFFCsVFGBwcsZqn0IJQoWpFdoLd_9PzONoxpmGepmGso-eH0djD9t_K5uLycu9-B6U2v44</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2509232066</pqid></control><display><type>article</type><title>If there were an effective pharmacotherapy for cocaine use disorder, what would it do?</title><source>MEDLINE</source><source>Access via Wiley Online Library</source><source>Web of Science - Science Citation Index Expanded - 2021<img src="https://exlibris-pub.s3.amazonaws.com/fromwos-v2.jpg" /></source><source>Web of Science - Social Sciences Citation Index – 2021<img src="https://exlibris-pub.s3.amazonaws.com/fromwos-v2.jpg" /></source><creator>Shoptaw, Steven ; Trivedi, Madhukar ; Potter, Jennifer S.</creator><creatorcontrib>Shoptaw, Steven ; Trivedi, Madhukar ; Potter, Jennifer S.</creatorcontrib><description>Although 30 years of research into an effective cocaine pharmacotherapy has yielded no treatments, knowledge gained doing this work underscores the importance of rigorous clinical design, of attention to medication adherence and of defining endpoints. The field needs a high‐risk/high‐reward strategy to engineer new compounds that help people to use less cocaine and to preserve gains made during treatment, particularly during lapse/relapse.</description><identifier>ISSN: 0965-2140</identifier><identifier>ISSN: 1360-0443</identifier><identifier>EISSN: 1360-0443</identifier><identifier>DOI: 10.1111/add.15310</identifier><identifier>PMID: 33269478</identifier><language>eng</language><publisher>HOBOKEN: Wiley</publisher><subject>Cocaine ; Cocaine-Related Disorders - drug therapy ; development ; Drug abuse ; Drug addiction ; Drug therapy ; Humans ; Life Sciences & Biomedicine ; Medical research ; medication ; outcomes ; Patient compliance ; Pharmacology ; pharmacotherapy ; Psychiatry ; Science & Technology ; Substance Abuse ; Substance abuse treatment ; Substance-Related Disorders</subject><ispartof>Addiction (Abingdon, England), 2021-04, Vol.116 (4), p.714-715</ispartof><rights>2020 Society for the Study of Addiction</rights><rights>2021 Society for the Study of Addiction</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>true</woscitedreferencessubscribed><woscitedreferencescount>2</woscitedreferencescount><woscitedreferencesoriginalsourcerecordid>wos000595015700001</woscitedreferencesoriginalsourcerecordid><citedby>FETCH-LOGICAL-c4430-142ae274ca69e0fca94bf3e1d3e3f77d7c6d15e616c1ca5b5f1560d9f8aadf893</citedby><cites>FETCH-LOGICAL-c4430-142ae274ca69e0fca94bf3e1d3e3f77d7c6d15e616c1ca5b5f1560d9f8aadf893</cites><orcidid>0000-0002-2983-1110 ; 0000-0002-3583-0026</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fadd.15310$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fadd.15310$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>230,315,782,786,887,1419,27931,27932,39264,39265,45581,45582</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33269478$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shoptaw, Steven</creatorcontrib><creatorcontrib>Trivedi, Madhukar</creatorcontrib><creatorcontrib>Potter, Jennifer S.</creatorcontrib><title>If there were an effective pharmacotherapy for cocaine use disorder, what would it do?</title><title>Addiction (Abingdon, England)</title><addtitle>ADDICTION</addtitle><addtitle>Addiction</addtitle><description>Although 30 years of research into an effective cocaine pharmacotherapy has yielded no treatments, knowledge gained doing this work underscores the importance of rigorous clinical design, of attention to medication adherence and of defining endpoints. The field needs a high‐risk/high‐reward strategy to engineer new compounds that help people to use less cocaine and to preserve gains made during treatment, particularly during lapse/relapse.</description><subject>Cocaine</subject><subject>Cocaine-Related Disorders - drug therapy</subject><subject>development</subject><subject>Drug abuse</subject><subject>Drug addiction</subject><subject>Drug therapy</subject><subject>Humans</subject><subject>Life Sciences & Biomedicine</subject><subject>Medical research</subject><subject>medication</subject><subject>outcomes</subject><subject>Patient compliance</subject><subject>Pharmacology</subject><subject>pharmacotherapy</subject><subject>Psychiatry</subject><subject>Science & Technology</subject><subject>Substance Abuse</subject><subject>Substance abuse treatment</subject><subject>Substance-Related Disorders</subject><issn>0965-2140</issn><issn>1360-0443</issn><issn>1360-0443</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>GIZIO</sourceid><sourceid>HGBXW</sourceid><sourceid>EIF</sourceid><recordid>eNqNkV1rFDEUhoModq1e-Ack4I2i0yaTr8mNUrZ-FAreqLchm5y4KbOTNZnpsv--2e66qCCYi-TAec7hCS9Czyk5o_WcW-_PqGCUPEAzyiRpCOfsIZoRLUXTUk5O0JNSbgghqtP8MTphrJWaq26Gvl8FPC4hA97sLjtgCAHcGG8Br5c2r6xLu75db3FIGbvkbBwATwWwjyVlD_kt3iztiDdp6j2OI_bp_VP0KNi-wLPDe4q-ffzwdf65uf7y6Wp-cd24akgaylsLreLOSg0kOKv5IjCgngELSnnlpKcCJJWOOisWIlAhidehs9aHTrNT9G6_dz0tVuAdDGO2vVnnuLJ5a5KN5s_OEJfmR7o1HaG0a0ld8OqwIKefE5TRrGJx0Pd2gDQV03IplWJc04q-_Au9SVMe6vdMK4huWUukrNTrPeVyKiVDOMpQYnZpmZqWuU-rsi9-tz-Sv-KpwJs9sIFFCsVFGBwcsZqn0IJQoWpFdoLd_9PzONoxpmGepmGso-eH0djD9t_K5uLycu9-B6U2v44</recordid><startdate>202104</startdate><enddate>202104</enddate><creator>Shoptaw, Steven</creator><creator>Trivedi, Madhukar</creator><creator>Potter, Jennifer S.</creator><general>Wiley</general><general>Blackwell Publishing Ltd</general><scope>17B</scope><scope>BLEPL</scope><scope>DTL</scope><scope>DVR</scope><scope>EGQ</scope><scope>GIZIO</scope><scope>HGBXW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>7TK</scope><scope>8BJ</scope><scope>FQK</scope><scope>JBE</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-2983-1110</orcidid><orcidid>https://orcid.org/0000-0002-3583-0026</orcidid></search><sort><creationdate>202104</creationdate><title>If there were an effective pharmacotherapy for cocaine use disorder, what would it do?</title><author>Shoptaw, Steven ; Trivedi, Madhukar ; Potter, Jennifer S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4430-142ae274ca69e0fca94bf3e1d3e3f77d7c6d15e616c1ca5b5f1560d9f8aadf893</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Cocaine</topic><topic>Cocaine-Related Disorders - drug therapy</topic><topic>development</topic><topic>Drug abuse</topic><topic>Drug addiction</topic><topic>Drug therapy</topic><topic>Humans</topic><topic>Life Sciences & Biomedicine</topic><topic>Medical research</topic><topic>medication</topic><topic>outcomes</topic><topic>Patient compliance</topic><topic>Pharmacology</topic><topic>pharmacotherapy</topic><topic>Psychiatry</topic><topic>Science & Technology</topic><topic>Substance Abuse</topic><topic>Substance abuse treatment</topic><topic>Substance-Related Disorders</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shoptaw, Steven</creatorcontrib><creatorcontrib>Trivedi, Madhukar</creatorcontrib><creatorcontrib>Potter, Jennifer S.</creatorcontrib><collection>Web of Knowledge</collection><collection>Web of Science Core Collection</collection><collection>Science Citation Index Expanded</collection><collection>Social Sciences Citation Index</collection><collection>Web of Science Primary (SCIE, SSCI & AHCI)</collection><collection>Web of Science - Social Sciences Citation Index – 2021</collection><collection>Web of Science - Science Citation Index Expanded - 2021</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>International Bibliography of the Social Sciences (IBSS)</collection><collection>International Bibliography of the Social Sciences</collection><collection>International Bibliography of the Social Sciences</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Addiction (Abingdon, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shoptaw, Steven</au><au>Trivedi, Madhukar</au><au>Potter, Jennifer S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>If there were an effective pharmacotherapy for cocaine use disorder, what would it do?</atitle><jtitle>Addiction (Abingdon, England)</jtitle><stitle>ADDICTION</stitle><addtitle>Addiction</addtitle><date>2021-04</date><risdate>2021</risdate><volume>116</volume><issue>4</issue><spage>714</spage><epage>715</epage><pages>714-715</pages><issn>0965-2140</issn><issn>1360-0443</issn><eissn>1360-0443</eissn><abstract>Although 30 years of research into an effective cocaine pharmacotherapy has yielded no treatments, knowledge gained doing this work underscores the importance of rigorous clinical design, of attention to medication adherence and of defining endpoints. The field needs a high‐risk/high‐reward strategy to engineer new compounds that help people to use less cocaine and to preserve gains made during treatment, particularly during lapse/relapse.</abstract><cop>HOBOKEN</cop><pub>Wiley</pub><pmid>33269478</pmid><doi>10.1111/add.15310</doi><orcidid>https://orcid.org/0000-0002-2983-1110</orcidid><orcidid>https://orcid.org/0000-0002-3583-0026</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0965-2140 |
| ispartof | Addiction (Abingdon, England), 2021-04, Vol.116 (4), p.714-715 |
| issn | 0965-2140 1360-0443 1360-0443 |
| language | eng |
| recordid | cdi_crossref_primary_10_1111_add_15310 |
| source | MEDLINE; Access via Wiley Online Library; Web of Science - Science Citation Index Expanded - 2021<img src="https://exlibris-pub.s3.amazonaws.com/fromwos-v2.jpg" />; Web of Science - Social Sciences Citation Index – 2021<img src="https://exlibris-pub.s3.amazonaws.com/fromwos-v2.jpg" /> |
| subjects | Cocaine Cocaine-Related Disorders - drug therapy development Drug abuse Drug addiction Drug therapy Humans Life Sciences & Biomedicine Medical research medication outcomes Patient compliance Pharmacology pharmacotherapy Psychiatry Science & Technology Substance Abuse Substance abuse treatment Substance-Related Disorders |
| title | If there were an effective pharmacotherapy for cocaine use disorder, what would it do? |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-08T10%3A36%3A22IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=If%20there%20were%20an%20effective%20pharmacotherapy%20for%20cocaine%20use%20disorder,%20what%20would%20it%20do?&rft.jtitle=Addiction%20(Abingdon,%20England)&rft.au=Shoptaw,%20Steven&rft.date=2021-04&rft.volume=116&rft.issue=4&rft.spage=714&rft.epage=715&rft.pages=714-715&rft.issn=0965-2140&rft.eissn=1360-0443&rft_id=info:doi/10.1111/add.15310&rft_dat=%3Cproquest_cross%3E2509232066%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2509232066&rft_id=info:pmid/33269478&rfr_iscdi=true |