If there were an effective pharmacotherapy for cocaine use disorder, what would it do?

Although 30 years of research into an effective cocaine pharmacotherapy has yielded no treatments, knowledge gained doing this work underscores the importance of rigorous clinical design, of attention to medication adherence and of defining endpoints. The field needs a high‐risk/high‐reward strategy...

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Veröffentlicht in:Addiction (Abingdon, England) England), 2021-04, Vol.116 (4), p.714-715
Hauptverfasser: Shoptaw, Steven, Trivedi, Madhukar, Potter, Jennifer S.
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container_title Addiction (Abingdon, England)
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creator Shoptaw, Steven
Trivedi, Madhukar
Potter, Jennifer S.
description Although 30 years of research into an effective cocaine pharmacotherapy has yielded no treatments, knowledge gained doing this work underscores the importance of rigorous clinical design, of attention to medication adherence and of defining endpoints. The field needs a high‐risk/high‐reward strategy to engineer new compounds that help people to use less cocaine and to preserve gains made during treatment, particularly during lapse/relapse.
doi_str_mv 10.1111/add.15310
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subjects Cocaine
Cocaine-Related Disorders - drug therapy
development
Drug abuse
Drug addiction
Drug therapy
Humans
Life Sciences & Biomedicine
Medical research
medication
outcomes
Patient compliance
Pharmacology
pharmacotherapy
Psychiatry
Science & Technology
Substance Abuse
Substance abuse treatment
Substance-Related Disorders
title If there were an effective pharmacotherapy for cocaine use disorder, what would it do?
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