Antimicrobial resistance genes in marine bacteria and human uropathogenic E scherichia coli from a region of intensive aquaculture

Antimicrobials are heavily used in C hilean salmon aquaculture. We previously found significant differences in antimicrobial‐resistant bacteria between sediments from an aquaculture and a non‐aquaculture site. We now show that levels of antimicrobial resistance genes ( ARG ) are significantly higher...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Environmental microbiology reports 2015-10, Vol.7 (5), p.803-809
Hauptverfasser: Tomova, Alexandra, Ivanova, Larisa, Buschmann, Alejandro H., Rioseco, Maria Luisa, Kalsi, Rajinder K., Godfrey, Henry P., Cabello, Felipe C.
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 809
container_issue 5
container_start_page 803
container_title Environmental microbiology reports
container_volume 7
creator Tomova, Alexandra
Ivanova, Larisa
Buschmann, Alejandro H.
Rioseco, Maria Luisa
Kalsi, Rajinder K.
Godfrey, Henry P.
Cabello, Felipe C.
description Antimicrobials are heavily used in C hilean salmon aquaculture. We previously found significant differences in antimicrobial‐resistant bacteria between sediments from an aquaculture and a non‐aquaculture site. We now show that levels of antimicrobial resistance genes ( ARG ) are significantly higher in antimicrobial‐selected marine bacteria than in unselected bacteria from these sites. While ARG in tetracycline‐ and florfenicol‐selected bacteria from aquaculture and non‐aquaculture sites were equally frequent, there were significantly more plasmid‐mediated quinolone resistance genes per bacterium and significantly higher numbers of qnrB genes in quinolone‐selected bacteria from the aquaculture site. Quinolone‐resistant urinary E scherichia coli from patients in the C hilean aquacultural region were significantly enriched for qnrB (including a novel qnrB gene), qnrS , qnrA and aac(6′)‐1b , compared with isolates from N ew Y ork C ity. Sequences of qnrA1 , qnrB1 and qnrS1 in quinolone‐resistant C hilean E . coli and C hilean marine bacteria were identical, suggesting horizontal gene transfer between antimicrobial‐resistant marine bacteria and human pathogens.
doi_str_mv 10.1111/1758-2229.12327
format Article
fullrecord <record><control><sourceid>crossref</sourceid><recordid>TN_cdi_crossref_primary_10_1111_1758_2229_12327</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>10_1111_1758_2229_12327</sourcerecordid><originalsourceid>FETCH-LOGICAL-c867-c53b32378f369873e27928d7c6d6262c45cd67a9d7314c679e2f971b8670bc4c3</originalsourceid><addsrcrecordid>eNpNkM1OwzAQhC0EEqVw5rovkDa2Ezs-VlX5kSpx6T1yNk5jlNjFTpC48uS4gBB72dVodqT5CLmn-YqmWVNZVhljTK0o40xekMWfcvnvviY3Mb7muShUzhbkc-MmO1oMvrF6gGCijZN2aOBonIlgHYw6WGeg0TiZYDVo10I_j9rBHPxJT71PVouwg4h9cmCfTOgHC13wI-gUerTege9S2mRctO8G9NuscR6mOZhbctXpIZq7370kh4fdYfuU7V8en7ebfYaVkBmWvOGMy6rjQlWSGyYVq1qJohVMMCxKbIXUqpWcFiikMqxTkjbpN2-wQL4k65_Y1DXGYLr6FGzq9lHTvD4TrM-M6jOj-psg_wL_fGVz</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Antimicrobial resistance genes in marine bacteria and human uropathogenic E scherichia coli from a region of intensive aquaculture</title><source>Wiley Online Library Journals Frontfile Complete</source><creator>Tomova, Alexandra ; Ivanova, Larisa ; Buschmann, Alejandro H. ; Rioseco, Maria Luisa ; Kalsi, Rajinder K. ; Godfrey, Henry P. ; Cabello, Felipe C.</creator><creatorcontrib>Tomova, Alexandra ; Ivanova, Larisa ; Buschmann, Alejandro H. ; Rioseco, Maria Luisa ; Kalsi, Rajinder K. ; Godfrey, Henry P. ; Cabello, Felipe C.</creatorcontrib><description>Antimicrobials are heavily used in C hilean salmon aquaculture. We previously found significant differences in antimicrobial‐resistant bacteria between sediments from an aquaculture and a non‐aquaculture site. We now show that levels of antimicrobial resistance genes ( ARG ) are significantly higher in antimicrobial‐selected marine bacteria than in unselected bacteria from these sites. While ARG in tetracycline‐ and florfenicol‐selected bacteria from aquaculture and non‐aquaculture sites were equally frequent, there were significantly more plasmid‐mediated quinolone resistance genes per bacterium and significantly higher numbers of qnrB genes in quinolone‐selected bacteria from the aquaculture site. Quinolone‐resistant urinary E scherichia coli from patients in the C hilean aquacultural region were significantly enriched for qnrB (including a novel qnrB gene), qnrS , qnrA and aac(6′)‐1b , compared with isolates from N ew Y ork C ity. Sequences of qnrA1 , qnrB1 and qnrS1 in quinolone‐resistant C hilean E . coli and C hilean marine bacteria were identical, suggesting horizontal gene transfer between antimicrobial‐resistant marine bacteria and human pathogens.</description><identifier>ISSN: 1758-2229</identifier><identifier>EISSN: 1758-2229</identifier><identifier>DOI: 10.1111/1758-2229.12327</identifier><language>eng</language><ispartof>Environmental microbiology reports, 2015-10, Vol.7 (5), p.803-809</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c867-c53b32378f369873e27928d7c6d6262c45cd67a9d7314c679e2f971b8670bc4c3</citedby><cites>FETCH-LOGICAL-c867-c53b32378f369873e27928d7c6d6262c45cd67a9d7314c679e2f971b8670bc4c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Tomova, Alexandra</creatorcontrib><creatorcontrib>Ivanova, Larisa</creatorcontrib><creatorcontrib>Buschmann, Alejandro H.</creatorcontrib><creatorcontrib>Rioseco, Maria Luisa</creatorcontrib><creatorcontrib>Kalsi, Rajinder K.</creatorcontrib><creatorcontrib>Godfrey, Henry P.</creatorcontrib><creatorcontrib>Cabello, Felipe C.</creatorcontrib><title>Antimicrobial resistance genes in marine bacteria and human uropathogenic E scherichia coli from a region of intensive aquaculture</title><title>Environmental microbiology reports</title><description>Antimicrobials are heavily used in C hilean salmon aquaculture. We previously found significant differences in antimicrobial‐resistant bacteria between sediments from an aquaculture and a non‐aquaculture site. We now show that levels of antimicrobial resistance genes ( ARG ) are significantly higher in antimicrobial‐selected marine bacteria than in unselected bacteria from these sites. While ARG in tetracycline‐ and florfenicol‐selected bacteria from aquaculture and non‐aquaculture sites were equally frequent, there were significantly more plasmid‐mediated quinolone resistance genes per bacterium and significantly higher numbers of qnrB genes in quinolone‐selected bacteria from the aquaculture site. Quinolone‐resistant urinary E scherichia coli from patients in the C hilean aquacultural region were significantly enriched for qnrB (including a novel qnrB gene), qnrS , qnrA and aac(6′)‐1b , compared with isolates from N ew Y ork C ity. Sequences of qnrA1 , qnrB1 and qnrS1 in quinolone‐resistant C hilean E . coli and C hilean marine bacteria were identical, suggesting horizontal gene transfer between antimicrobial‐resistant marine bacteria and human pathogens.</description><issn>1758-2229</issn><issn>1758-2229</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNpNkM1OwzAQhC0EEqVw5rovkDa2Ezs-VlX5kSpx6T1yNk5jlNjFTpC48uS4gBB72dVodqT5CLmn-YqmWVNZVhljTK0o40xekMWfcvnvviY3Mb7muShUzhbkc-MmO1oMvrF6gGCijZN2aOBonIlgHYw6WGeg0TiZYDVo10I_j9rBHPxJT71PVouwg4h9cmCfTOgHC13wI-gUerTege9S2mRctO8G9NuscR6mOZhbctXpIZq7370kh4fdYfuU7V8en7ebfYaVkBmWvOGMy6rjQlWSGyYVq1qJohVMMCxKbIXUqpWcFiikMqxTkjbpN2-wQL4k65_Y1DXGYLr6FGzq9lHTvD4TrM-M6jOj-psg_wL_fGVz</recordid><startdate>201510</startdate><enddate>201510</enddate><creator>Tomova, Alexandra</creator><creator>Ivanova, Larisa</creator><creator>Buschmann, Alejandro H.</creator><creator>Rioseco, Maria Luisa</creator><creator>Kalsi, Rajinder K.</creator><creator>Godfrey, Henry P.</creator><creator>Cabello, Felipe C.</creator><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>201510</creationdate><title>Antimicrobial resistance genes in marine bacteria and human uropathogenic E scherichia coli from a region of intensive aquaculture</title><author>Tomova, Alexandra ; Ivanova, Larisa ; Buschmann, Alejandro H. ; Rioseco, Maria Luisa ; Kalsi, Rajinder K. ; Godfrey, Henry P. ; Cabello, Felipe C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c867-c53b32378f369873e27928d7c6d6262c45cd67a9d7314c679e2f971b8670bc4c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tomova, Alexandra</creatorcontrib><creatorcontrib>Ivanova, Larisa</creatorcontrib><creatorcontrib>Buschmann, Alejandro H.</creatorcontrib><creatorcontrib>Rioseco, Maria Luisa</creatorcontrib><creatorcontrib>Kalsi, Rajinder K.</creatorcontrib><creatorcontrib>Godfrey, Henry P.</creatorcontrib><creatorcontrib>Cabello, Felipe C.</creatorcontrib><collection>CrossRef</collection><jtitle>Environmental microbiology reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tomova, Alexandra</au><au>Ivanova, Larisa</au><au>Buschmann, Alejandro H.</au><au>Rioseco, Maria Luisa</au><au>Kalsi, Rajinder K.</au><au>Godfrey, Henry P.</au><au>Cabello, Felipe C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antimicrobial resistance genes in marine bacteria and human uropathogenic E scherichia coli from a region of intensive aquaculture</atitle><jtitle>Environmental microbiology reports</jtitle><date>2015-10</date><risdate>2015</risdate><volume>7</volume><issue>5</issue><spage>803</spage><epage>809</epage><pages>803-809</pages><issn>1758-2229</issn><eissn>1758-2229</eissn><abstract>Antimicrobials are heavily used in C hilean salmon aquaculture. We previously found significant differences in antimicrobial‐resistant bacteria between sediments from an aquaculture and a non‐aquaculture site. We now show that levels of antimicrobial resistance genes ( ARG ) are significantly higher in antimicrobial‐selected marine bacteria than in unselected bacteria from these sites. While ARG in tetracycline‐ and florfenicol‐selected bacteria from aquaculture and non‐aquaculture sites were equally frequent, there were significantly more plasmid‐mediated quinolone resistance genes per bacterium and significantly higher numbers of qnrB genes in quinolone‐selected bacteria from the aquaculture site. Quinolone‐resistant urinary E scherichia coli from patients in the C hilean aquacultural region were significantly enriched for qnrB (including a novel qnrB gene), qnrS , qnrA and aac(6′)‐1b , compared with isolates from N ew Y ork C ity. Sequences of qnrA1 , qnrB1 and qnrS1 in quinolone‐resistant C hilean E . coli and C hilean marine bacteria were identical, suggesting horizontal gene transfer between antimicrobial‐resistant marine bacteria and human pathogens.</abstract><doi>10.1111/1758-2229.12327</doi><tpages>7</tpages></addata></record>
fulltext fulltext
identifier ISSN: 1758-2229
ispartof Environmental microbiology reports, 2015-10, Vol.7 (5), p.803-809
issn 1758-2229
1758-2229
language eng
recordid cdi_crossref_primary_10_1111_1758_2229_12327
source Wiley Online Library Journals Frontfile Complete
title Antimicrobial resistance genes in marine bacteria and human uropathogenic E scherichia coli from a region of intensive aquaculture
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-29T01%3A16%3A22IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-crossref&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Antimicrobial%20resistance%20genes%20in%20marine%20bacteria%20and%20human%20uropathogenic%20E%20scherichia%20coli%20from%20a%20region%20of%20intensive%20aquaculture&rft.jtitle=Environmental%20microbiology%20reports&rft.au=Tomova,%20Alexandra&rft.date=2015-10&rft.volume=7&rft.issue=5&rft.spage=803&rft.epage=809&rft.pages=803-809&rft.issn=1758-2229&rft.eissn=1758-2229&rft_id=info:doi/10.1111/1758-2229.12327&rft_dat=%3Ccrossref%3E10_1111_1758_2229_12327%3C/crossref%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true