Characterization and Subcellular Localization of Human Pmel 17/silver, a 100-kDa (Pre)Melanosomal Membrane Protein Associated With 5,6,-Dihydroxyindole-2-Carboxylic Acid (DHICA) Converting Activity

Pmel 17 is preferentially expressed in pigment cells in a manner suggestive of involvement in melanin bio-synthesis. The gene is identical to the silver (si) pigmentation locus in mice. We now have produced a recombinant glutathione-S-transferase-human Pmel 17 fusion protein and raised polyclonal an...

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Veröffentlicht in:	Journal of investigative dermatology 1996-04, Vol.106 (4), p.605-610
Hauptverfasser:	Lee, Zang H., Hou, Ling, Moellmann, Gisela, Kuklinska, Elizabeth, Antol, Kathleen, Fraser, Malcolm, Halaban, Ruth, Kwon, Byoung S.
Format:	Artikel
Sprache:	eng
Schlagworte:	HMB 45 melanocyte melanoma antigen NK1-beteb tyrosinase-related proteins
Online-Zugang:	Volltext
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