Growth Suppression of Hamster Flank Organs by Topical Application of γ-Linolenic and Other Fatty Acid Inhibitors of 5α-Reductase

Certain unsaturated aliphatic fatty acids, such as γ-linolenic acid, inhibit 5α-reductase activity in vitro and in vivo. Hamster flank organ growth, as measured by the increase in the area of pigmented macule, is dependent on androgen. When one of the paired flank organs of a castrated hamster was t...

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Veröffentlicht in:Journal of investigative dermatology 1997-08, Vol.109 (2), p.152-157
Hauptverfasser: Liang, Tehming, Liao, Shutsung
Format: Artikel
Sprache:eng
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