1.7-Micron Optical Coherence Tomography Angiography for Characterization of Skin Lesions-A Feasibility Study
Optical coherence tomography (OCT) is a non-invasive diagnostic method that offers real-time visualization of the layered architecture of the skin in vivo . The 1.7-micron OCT system has been applied in cardiology, gynecology and dermatology, demonstrating an improved penetration depth in contrast t...
Gespeichert in:
| Veröffentlicht in: | IEEE transactions on medical imaging 2021-09, Vol.40 (9), p.2507-2512 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2512 |
|---|---|
| container_issue | 9 |
| container_start_page | 2507 |
| container_title | IEEE transactions on medical imaging |
| container_volume | 40 |
| creator | Li, Yan Murthy, Raksha Sreeramachandra Zhu, Yirui Zhang, Fengyi Tang, Jianing Mehrabi, Joseph N. Kelly, Kristen M. Chen, Zhongping |
| description | Optical coherence tomography (OCT) is a non-invasive diagnostic method that offers real-time visualization of the layered architecture of the skin in vivo . The 1.7-micron OCT system has been applied in cardiology, gynecology and dermatology, demonstrating an improved penetration depth in contrast to conventional 1.3-micron OCT. To further extend the capability, we developed a 1.7-micron OCT/OCT angiography (OCTA) system that allows for visualization of both morphology and microvasculature in the deeper layers of the skin. Using this imaging system, we imaged human skin with different benign lesions and described the corresponding features of both structure and vasculature. The significantly improved imaging depth and additional functional information suggest that the 1.7-micron OCTA system has great potential to advance both dermatological clinical and research settings for characterization of benign and cancerous skin lesions. |
| doi_str_mv | 10.1109/TMI.2021.3081066 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_RIE</sourceid><recordid>TN_cdi_crossref_primary_10_1109_TMI_2021_3081066</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><ieee_id>9432926</ieee_id><sourcerecordid>2568063433</sourcerecordid><originalsourceid>FETCH-LOGICAL-c444t-17fb6099791def715f91d464b084eca741213174c453f1596149b8b132e03d4a3</originalsourceid><addsrcrecordid>eNpdkc1rGzEQxUVpady090KhCHLpZV2NPnalS8GYpg045BAXehPa9aytdL1ypd2C-9dXxo5JetKI-b3HzDxC3gObAjDzeXl7M-WMw1QwDawsX5AJKKULruTPl2TCeKULxkp-Qd6k9MAYSMXMa3IhhDFGQzUhHUyr4tY3MfT0bjf4xnV0HjYYsW-QLsM2rKPbbfZ01q_9Y92GSOcbF10zYPR_3eCzOrT0_pfv6QJT_qZiRq_RJV_7zg97ej-Mq_1b8qp1XcJ3p_eS_Lj-upx_LxZ3327ms0XRSCmHAqq2LpkxlYEVthWoNheylDXTEhtXSeAgoJKNVKIFZUqQptY1CI5MrKQTl-TL0Xc31ltcNdgP0XV2F_3Wxb0Nztvnnd5v7Dr8sVoLqbTIBp9OBjH8HjENdutTg13negxjslxxrUEofkCv_kMfwhj7vF6mSs1KIcWBYkcqHzqliO15GGD2EKXNUdpDlPYUZZZ8fLrEWfCYXQY-HAGPiOe2kYIbXop_j5iiWg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2568063433</pqid></control><display><type>article</type><title>1.7-Micron Optical Coherence Tomography Angiography for Characterization of Skin Lesions-A Feasibility Study</title><source>IEEE Electronic Library (IEL)</source><creator>Li, Yan ; Murthy, Raksha Sreeramachandra ; Zhu, Yirui ; Zhang, Fengyi ; Tang, Jianing ; Mehrabi, Joseph N. ; Kelly, Kristen M. ; Chen, Zhongping</creator><creatorcontrib>Li, Yan ; Murthy, Raksha Sreeramachandra ; Zhu, Yirui ; Zhang, Fengyi ; Tang, Jianing ; Mehrabi, Joseph N. ; Kelly, Kristen M. ; Chen, Zhongping</creatorcontrib><description>Optical coherence tomography (OCT) is a non-invasive diagnostic method that offers real-time visualization of the layered architecture of the skin in vivo . The 1.7-micron OCT system has been applied in cardiology, gynecology and dermatology, demonstrating an improved penetration depth in contrast to conventional 1.3-micron OCT. To further extend the capability, we developed a 1.7-micron OCT/OCT angiography (OCTA) system that allows for visualization of both morphology and microvasculature in the deeper layers of the skin. Using this imaging system, we imaged human skin with different benign lesions and described the corresponding features of both structure and vasculature. The significantly improved imaging depth and additional functional information suggest that the 1.7-micron OCTA system has great potential to advance both dermatological clinical and research settings for characterization of benign and cancerous skin lesions.</description><identifier>ISSN: 0278-0062</identifier><identifier>EISSN: 1558-254X</identifier><identifier>DOI: 10.1109/TMI.2021.3081066</identifier><identifier>PMID: 33999817</identifier><identifier>CODEN: ITMID4</identifier><language>eng</language><publisher>United States: IEEE</publisher><subject>17-micron ; Angiography ; Cardiology ; clinical diagnosis ; Dermatology ; Feasibility Studies ; Green products ; Gynecology ; Humans ; Imaging ; Lesions ; Medical diagnosis ; Medical imaging ; Microvasculature ; Morphology ; OCT angiography ; Optical Coherence Tomography ; Penetration depth ; Skin ; Skin - diagnostic imaging ; Skin cancer ; Skin diseases ; Skin Diseases - diagnostic imaging ; Skin lesions ; Spatial resolution ; Three-dimensional displays ; Tomography ; Tomography, Optical Coherence ; Visualization</subject><ispartof>IEEE transactions on medical imaging, 2021-09, Vol.40 (9), p.2507-2512</ispartof><rights>Copyright The Institute of Electrical and Electronics Engineers, Inc. (IEEE) 2021</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c444t-17fb6099791def715f91d464b084eca741213174c453f1596149b8b132e03d4a3</citedby><cites>FETCH-LOGICAL-c444t-17fb6099791def715f91d464b084eca741213174c453f1596149b8b132e03d4a3</cites><orcidid>0000-0002-4584-4560 ; 0000-0002-5313-8068 ; 0000-0002-3468-9235 ; 0000-0001-9079-5799</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://ieeexplore.ieee.org/document/9432926$$EHTML$$P50$$Gieee$$H</linktohtml><link.rule.ids>230,314,778,782,794,883,27907,27908,54741</link.rule.ids><linktorsrc>$$Uhttps://ieeexplore.ieee.org/document/9432926$$EView_record_in_IEEE$$FView_record_in_$$GIEEE</linktorsrc><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33999817$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Li, Yan</creatorcontrib><creatorcontrib>Murthy, Raksha Sreeramachandra</creatorcontrib><creatorcontrib>Zhu, Yirui</creatorcontrib><creatorcontrib>Zhang, Fengyi</creatorcontrib><creatorcontrib>Tang, Jianing</creatorcontrib><creatorcontrib>Mehrabi, Joseph N.</creatorcontrib><creatorcontrib>Kelly, Kristen M.</creatorcontrib><creatorcontrib>Chen, Zhongping</creatorcontrib><title>1.7-Micron Optical Coherence Tomography Angiography for Characterization of Skin Lesions-A Feasibility Study</title><title>IEEE transactions on medical imaging</title><addtitle>TMI</addtitle><addtitle>IEEE Trans Med Imaging</addtitle><description>Optical coherence tomography (OCT) is a non-invasive diagnostic method that offers real-time visualization of the layered architecture of the skin in vivo . The 1.7-micron OCT system has been applied in cardiology, gynecology and dermatology, demonstrating an improved penetration depth in contrast to conventional 1.3-micron OCT. To further extend the capability, we developed a 1.7-micron OCT/OCT angiography (OCTA) system that allows for visualization of both morphology and microvasculature in the deeper layers of the skin. Using this imaging system, we imaged human skin with different benign lesions and described the corresponding features of both structure and vasculature. The significantly improved imaging depth and additional functional information suggest that the 1.7-micron OCTA system has great potential to advance both dermatological clinical and research settings for characterization of benign and cancerous skin lesions.</description><subject>17-micron</subject><subject>Angiography</subject><subject>Cardiology</subject><subject>clinical diagnosis</subject><subject>Dermatology</subject><subject>Feasibility Studies</subject><subject>Green products</subject><subject>Gynecology</subject><subject>Humans</subject><subject>Imaging</subject><subject>Lesions</subject><subject>Medical diagnosis</subject><subject>Medical imaging</subject><subject>Microvasculature</subject><subject>Morphology</subject><subject>OCT angiography</subject><subject>Optical Coherence Tomography</subject><subject>Penetration depth</subject><subject>Skin</subject><subject>Skin - diagnostic imaging</subject><subject>Skin cancer</subject><subject>Skin diseases</subject><subject>Skin Diseases - diagnostic imaging</subject><subject>Skin lesions</subject><subject>Spatial resolution</subject><subject>Three-dimensional displays</subject><subject>Tomography</subject><subject>Tomography, Optical Coherence</subject><subject>Visualization</subject><issn>0278-0062</issn><issn>1558-254X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>RIE</sourceid><sourceid>EIF</sourceid><recordid>eNpdkc1rGzEQxUVpady090KhCHLpZV2NPnalS8GYpg045BAXehPa9aytdL1ypd2C-9dXxo5JetKI-b3HzDxC3gObAjDzeXl7M-WMw1QwDawsX5AJKKULruTPl2TCeKULxkp-Qd6k9MAYSMXMa3IhhDFGQzUhHUyr4tY3MfT0bjf4xnV0HjYYsW-QLsM2rKPbbfZ01q_9Y92GSOcbF10zYPR_3eCzOrT0_pfv6QJT_qZiRq_RJV_7zg97ej-Mq_1b8qp1XcJ3p_eS_Lj-upx_LxZ3327ms0XRSCmHAqq2LpkxlYEVthWoNheylDXTEhtXSeAgoJKNVKIFZUqQptY1CI5MrKQTl-TL0Xc31ltcNdgP0XV2F_3Wxb0Nztvnnd5v7Dr8sVoLqbTIBp9OBjH8HjENdutTg13negxjslxxrUEofkCv_kMfwhj7vF6mSs1KIcWBYkcqHzqliO15GGD2EKXNUdpDlPYUZZZ8fLrEWfCYXQY-HAGPiOe2kYIbXop_j5iiWg</recordid><startdate>20210901</startdate><enddate>20210901</enddate><creator>Li, Yan</creator><creator>Murthy, Raksha Sreeramachandra</creator><creator>Zhu, Yirui</creator><creator>Zhang, Fengyi</creator><creator>Tang, Jianing</creator><creator>Mehrabi, Joseph N.</creator><creator>Kelly, Kristen M.</creator><creator>Chen, Zhongping</creator><general>IEEE</general><general>The Institute of Electrical and Electronics Engineers, Inc. (IEEE)</general><scope>97E</scope><scope>RIA</scope><scope>RIE</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QF</scope><scope>7QO</scope><scope>7QQ</scope><scope>7SC</scope><scope>7SE</scope><scope>7SP</scope><scope>7SR</scope><scope>7TA</scope><scope>7TB</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>F28</scope><scope>FR3</scope><scope>H8D</scope><scope>JG9</scope><scope>JQ2</scope><scope>KR7</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>NAPCQ</scope><scope>P64</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-4584-4560</orcidid><orcidid>https://orcid.org/0000-0002-5313-8068</orcidid><orcidid>https://orcid.org/0000-0002-3468-9235</orcidid><orcidid>https://orcid.org/0000-0001-9079-5799</orcidid></search><sort><creationdate>20210901</creationdate><title>1.7-Micron Optical Coherence Tomography Angiography for Characterization of Skin Lesions-A Feasibility Study</title><author>Li, Yan ; Murthy, Raksha Sreeramachandra ; Zhu, Yirui ; Zhang, Fengyi ; Tang, Jianing ; Mehrabi, Joseph N. ; Kelly, Kristen M. ; Chen, Zhongping</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c444t-17fb6099791def715f91d464b084eca741213174c453f1596149b8b132e03d4a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>17-micron</topic><topic>Angiography</topic><topic>Cardiology</topic><topic>clinical diagnosis</topic><topic>Dermatology</topic><topic>Feasibility Studies</topic><topic>Green products</topic><topic>Gynecology</topic><topic>Humans</topic><topic>Imaging</topic><topic>Lesions</topic><topic>Medical diagnosis</topic><topic>Medical imaging</topic><topic>Microvasculature</topic><topic>Morphology</topic><topic>OCT angiography</topic><topic>Optical Coherence Tomography</topic><topic>Penetration depth</topic><topic>Skin</topic><topic>Skin - diagnostic imaging</topic><topic>Skin cancer</topic><topic>Skin diseases</topic><topic>Skin Diseases - diagnostic imaging</topic><topic>Skin lesions</topic><topic>Spatial resolution</topic><topic>Three-dimensional displays</topic><topic>Tomography</topic><topic>Tomography, Optical Coherence</topic><topic>Visualization</topic><toplevel>online_resources</toplevel><creatorcontrib>Li, Yan</creatorcontrib><creatorcontrib>Murthy, Raksha Sreeramachandra</creatorcontrib><creatorcontrib>Zhu, Yirui</creatorcontrib><creatorcontrib>Zhang, Fengyi</creatorcontrib><creatorcontrib>Tang, Jianing</creatorcontrib><creatorcontrib>Mehrabi, Joseph N.</creatorcontrib><creatorcontrib>Kelly, Kristen M.</creatorcontrib><creatorcontrib>Chen, Zhongping</creatorcontrib><collection>IEEE All-Society Periodicals Package (ASPP) 2005-present</collection><collection>IEEE All-Society Periodicals Package (ASPP) 1998-Present</collection><collection>IEEE Electronic Library (IEL)</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Aluminium Industry Abstracts</collection><collection>Biotechnology Research Abstracts</collection><collection>Ceramic Abstracts</collection><collection>Computer and Information Systems Abstracts</collection><collection>Corrosion Abstracts</collection><collection>Electronics & Communications Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Materials Business File</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Aerospace Database</collection><collection>Materials Research Database</collection><collection>ProQuest Computer Science Collection</collection><collection>Civil Engineering Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Computer and Information Systems Abstracts Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>IEEE transactions on medical imaging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Li, Yan</au><au>Murthy, Raksha Sreeramachandra</au><au>Zhu, Yirui</au><au>Zhang, Fengyi</au><au>Tang, Jianing</au><au>Mehrabi, Joseph N.</au><au>Kelly, Kristen M.</au><au>Chen, Zhongping</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>1.7-Micron Optical Coherence Tomography Angiography for Characterization of Skin Lesions-A Feasibility Study</atitle><jtitle>IEEE transactions on medical imaging</jtitle><stitle>TMI</stitle><addtitle>IEEE Trans Med Imaging</addtitle><date>2021-09-01</date><risdate>2021</risdate><volume>40</volume><issue>9</issue><spage>2507</spage><epage>2512</epage><pages>2507-2512</pages><issn>0278-0062</issn><eissn>1558-254X</eissn><coden>ITMID4</coden><abstract>Optical coherence tomography (OCT) is a non-invasive diagnostic method that offers real-time visualization of the layered architecture of the skin in vivo . The 1.7-micron OCT system has been applied in cardiology, gynecology and dermatology, demonstrating an improved penetration depth in contrast to conventional 1.3-micron OCT. To further extend the capability, we developed a 1.7-micron OCT/OCT angiography (OCTA) system that allows for visualization of both morphology and microvasculature in the deeper layers of the skin. Using this imaging system, we imaged human skin with different benign lesions and described the corresponding features of both structure and vasculature. The significantly improved imaging depth and additional functional information suggest that the 1.7-micron OCTA system has great potential to advance both dermatological clinical and research settings for characterization of benign and cancerous skin lesions.</abstract><cop>United States</cop><pub>IEEE</pub><pmid>33999817</pmid><doi>10.1109/TMI.2021.3081066</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0002-4584-4560</orcidid><orcidid>https://orcid.org/0000-0002-5313-8068</orcidid><orcidid>https://orcid.org/0000-0002-3468-9235</orcidid><orcidid>https://orcid.org/0000-0001-9079-5799</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | ISSN: 0278-0062 |
| ispartof | IEEE transactions on medical imaging, 2021-09, Vol.40 (9), p.2507-2512 |
| issn | 0278-0062 1558-254X |
| language | eng |
| recordid | cdi_crossref_primary_10_1109_TMI_2021_3081066 |
| source | IEEE Electronic Library (IEL) |
| subjects | 17-micron Angiography Cardiology clinical diagnosis Dermatology Feasibility Studies Green products Gynecology Humans Imaging Lesions Medical diagnosis Medical imaging Microvasculature Morphology OCT angiography Optical Coherence Tomography Penetration depth Skin Skin - diagnostic imaging Skin cancer Skin diseases Skin Diseases - diagnostic imaging Skin lesions Spatial resolution Three-dimensional displays Tomography Tomography, Optical Coherence Visualization |
| title | 1.7-Micron Optical Coherence Tomography Angiography for Characterization of Skin Lesions-A Feasibility Study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-17T04%3A10%3A24IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_RIE&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=1.7-Micron%20Optical%20Coherence%20Tomography%20Angiography%20for%20Characterization%20of%20Skin%20Lesions-A%20Feasibility%20Study&rft.jtitle=IEEE%20transactions%20on%20medical%20imaging&rft.au=Li,%20Yan&rft.date=2021-09-01&rft.volume=40&rft.issue=9&rft.spage=2507&rft.epage=2512&rft.pages=2507-2512&rft.issn=0278-0062&rft.eissn=1558-254X&rft.coden=ITMID4&rft_id=info:doi/10.1109/TMI.2021.3081066&rft_dat=%3Cproquest_RIE%3E2568063433%3C/proquest_RIE%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2568063433&rft_id=info:pmid/33999817&rft_ieee_id=9432926&rfr_iscdi=true |