Analytical calculation of volumes-of-intersection for iterative, fully 3-D PET reconstruction

Use of iterative algorithms to reconstruct three-dimensional (3-D) positron emission tomography (PET) data requires the computation of the system probability matrix. The pure geometrical contribution can easily be approximated by the length-of-intersection (LOI) between lines-of-response (LOR) and i...

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Veröffentlicht in:IEEE transactions on medical imaging 2006-10, Vol.25 (10), p.1363-1369
Hauptverfasser: Scheins, J.J., Boschen, F., Herzog, H.
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Boschen, F.
Herzog, H.
description Use of iterative algorithms to reconstruct three-dimensional (3-D) positron emission tomography (PET) data requires the computation of the system probability matrix. The pure geometrical contribution can easily be approximated by the length-of-intersection (LOI) between lines-of-response (LOR) and individual voxels. However, more accurate geometrical projectors are desirable. Therefore, we have developed a fast method for the analytical calculation of the 3-D shape and volume of volumes-of-intersection (VOI). This method provides an alternative robust projector with a uniformly continuous sampling of the image space. The enhanced calculation effort is facilitated by using several speedup techniques. Exploiting intrinsic symmetry relations and the sparseness of the system matrix allows to create an efficiently compressed matrix which can be precomputed and completely stored in memory. In addition, a new voxel addressing scheme has been implemented. This scheme avoids time-consuming symmetry transformations of voxel addresses by using an octant-wise symmetrically ordered field of voxels. The above methods have been applied for a fully 3-D, iterative reconstruction of 3-D sinograms recorded with a Siemens/CTI ECAT HR+ PET scanner. A comparison of the performance of the reconstruction using LOI weighting and VOI weighting is presented
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subjects Algorithm design and analysis
Algorithms
Biomedical imaging
Brain - diagnostic imaging
Humans
Image Enhancement - methods
Image Interpretation, Computer-Assisted - methods
Image quality
Image reconstruction
Image sampling
Imaging, Three-Dimensional - methods
Information Storage and Retrieval - methods
Iterative methods
Iterative reconstruction
memory-resident system matrix
Positron emission tomography
positron emission tomography (PET)
Positron-Emission Tomography - methods
Probability
Reproducibility of Results
Sensitivity and Specificity
Shape
Studies
Symmetric matrices
symmetries
volumes-of-intersection (VOI)
title Analytical calculation of volumes-of-intersection for iterative, fully 3-D PET reconstruction
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