Maximum Covering Subtrees for Phylogenetic Networks

Tree-based phylogenetic networks, which may be roughly defined as leaf-labeled networks built by adding arcs only between the original tree edges, have elegant properties for modeling evolutionary histories. We answer an open question of Francis, Semple, and Steel about the complexity of determining...

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Veröffentlicht in:IEEE/ACM transactions on computational biology and bioinformatics 2021-11, Vol.18 (6), p.2823-2827
Hauptverfasser: Davidov, Nathan, Hernandez, Amanda, Jian, Justin, McKenna, Patrick, Medlin, K.A., Mojumder, Roadra, Owen, Megan, Quijano, Andrew, Rodriguez, Amanda, St. John, Katherine, Thai, Katherine, Uraga, Meliza
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container_title IEEE/ACM transactions on computational biology and bioinformatics
container_volume 18
creator Davidov, Nathan
Hernandez, Amanda
Jian, Justin
McKenna, Patrick
Medlin, K.A.
Mojumder, Roadra
Owen, Megan
Quijano, Andrew
Rodriguez, Amanda
St. John, Katherine
Thai, Katherine
Uraga, Meliza
description Tree-based phylogenetic networks, which may be roughly defined as leaf-labeled networks built by adding arcs only between the original tree edges, have elegant properties for modeling evolutionary histories. We answer an open question of Francis, Semple, and Steel about the complexity of determining how far a phylogenetic network is from being tree-based, including non-binary phylogenetic networks. We show that finding a phylogenetic tree covering the maximum number of nodes in a phylogenetic network can be computed in polynomial time via an encoding into a minimum-cost flow problem.
doi_str_mv 10.1109/TCBB.2020.3040910
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subjects Algorithms
complexity
Complexity theory
Computational Biology - methods
Encoding
Evolution, Molecular
flow networks
Models, Genetic
Networks
phylogenetic networks
Phylogenetics
Phylogeny
Polynomials
trees
title Maximum Covering Subtrees for Phylogenetic Networks
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