Signal Analysis and Liver Tumor Discrimination by Using a High-Tc SQUID-Based Low-Field NMR System in Hospital

In this paper, a high-T c SQUID-based nuclear magnetic resonance (NMR) spectrometer was set up in National Taiwan University Hospital to discriminate liver tumor. In order to overcome the surrounding noise, a four-layer Al shielded box and a cylindrical magnetic shield were employed to avoid the ele...

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Veröffentlicht in:	IEEE transactions on applied superconductivity 2015-06, Vol.25 (3), p.1-4
Hauptverfasser:	Liao, Shu-Hsien, Chieh, Jen-Jie, Chou, Yen-Ting, Wang, Ming-Wei, Chen, Hsin-Hsien, Huang, Kai-Wen, Yang, Hong-Chang, Horng, Herng-Er
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Sprache:	eng
Schlagworte:	Coils liver tumor Magnetic fields Magnetic resonance imaging Nuclear magnetic resonance SQUID SQUIDs Tumors Ultra-low-field NMR
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container_title	IEEE transactions on applied superconductivity
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creator	Liao, Shu-Hsien Chieh, Jen-Jie Chou, Yen-Ting Wang, Ming-Wei Chen, Hsin-Hsien Huang, Kai-Wen Yang, Hong-Chang Horng, Herng-Er
description	In this paper, a high-T c SQUID-based nuclear magnetic resonance (NMR) spectrometer was set up in National Taiwan University Hospital to discriminate liver tumor. In order to overcome the surrounding noise, a four-layer Al shielded box and a cylindrical magnetic shield were employed to avoid the electromagnetic noise in the coils part and the SQUID part, respectively. For NMR measurement, the larmor frequency is varying with time due to the variation of static field in hospital. Therefore, the time-domain frequency adjusted average method guided by a fluxgate was used to correct the frequency variation and average the NMR signal in the time domain. For tumor discrimination, the T 1 relaxation times of normal tissue and tumor tissue were demonstrated. Our high-T c SQUID-based low-field MRI system shows the feasibility for biomedical application in a clinic environment.
doi_str_mv	10.1109/TASC.2015.2393633
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subjects	Coils liver tumor Magnetic fields Magnetic resonance imaging Nuclear magnetic resonance SQUID SQUIDs Tumors Ultra-low-field NMR
title	Signal Analysis and Liver Tumor Discrimination by Using a High-Tc SQUID-Based Low-Field NMR System in Hospital
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