Detection of DNA Hybridization Beyond the Debye Screening Length by CMOS Capacitive Sensors

Capacitive sensors are very promising to provide label-free and real-time biological detection for point-of-care diagnostic applications. However, the Debye charge screening effect severely hinders the detection under high ionic strength condition, such as in human serum. Therefore, most measurement...

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Veröffentlicht in:	IEEE electron device letters 2022-08, Vol.43 (8), p.1319-1322
Hauptverfasser:	Lin, Chang-Hung, Lee, Yuan-Chieh, Yang, Chia-Min, Lu, Michael S.-C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biosensors Capacitance Capacitive sensors CMOS Debye length Deoxyribonucleic acid DNA Electric fields Electrodes Frequency modulation interdigitated electrodes Response time Screening Sensors
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