Pre-Clinical Translation of Second Harmonic Microscopy of Meniscal and Articular Cartilage Using a Prototype Nonlinear Microendoscope

Previous studies using nonlinear microscopy have demonstrated that osteoarthritis (OA) is characterized by the gradual replacement of Type II collagen with Type I collagen. The objective of this study was to develop a prototype nonlinear laser scanning microendoscope capable of resolving the structu...

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Veröffentlicht in:	IEEE journal of translational engineering in health and medicine 2019-01, Vol.7, p.1-11
Hauptverfasser:	Baskey, Stephen J., Andreana, Marco, Lanteigne, Eric, Ridsdale, Andrew, Stolow, Albert, Schweitzer, Mark E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Arthroscopy Backscattering Biomedical materials Biomedical optical imaging Cartilage Collagen diagnostics Femtosecond pulsed lasers Fiber nonlinear optics Fiber optics histology Image quality In vivo methods and tests Knee Lasers Microscopy Optical fibers Optical imaging orthopaedics osteoarthritis Prototypes Scanning microscopy second harmonic imaging Sheaths surgical assist devices
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