A Non-Invasive Flexible Glucose Monitoring Sensor Using a Broadband Reject Filter
In this paper, a novel, highly accurate, non-invasive glucose-monitoring sensor that is based on a flexible broadband reject filter is presented. The filter topology comprises a tapered feed line at a top layer that excites four open loop resonators on the bottom layer. The broadband reject response...
Gespeichert in:
| Veröffentlicht in: | IEEE journal of electromagnetics, RF and microwaves in medicine and biology RF and microwaves in medicine and biology, 2021-06, Vol.5 (2), p.139-147 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 147 |
|---|---|
| container_issue | 2 |
| container_start_page | 139 |
| container_title | IEEE journal of electromagnetics, RF and microwaves in medicine and biology |
| container_volume | 5 |
| creator | Bteich, Moussa Hanna, Jessica Costantine, Joseph Kanj, Rouwaida Tawk, Youssef Ramadan, Ali H. Eid, Assaad A. |
| description | In this paper, a novel, highly accurate, non-invasive glucose-monitoring sensor that is based on a flexible broadband reject filter is presented. The filter topology comprises a tapered feed line at a top layer that excites four open loop resonators on the bottom layer. The broadband reject response is achieved by relying on a modified log-periodic distribution of the open loop resonators. The embedded resonators are reduced in size and are designed to exhibit an enhanced sensitivity to track the variations of the glucose level across the 1.25-2.65 GHz frequency span. The proposed flexible filter is tested within in-vitro, ex-vivo and in-vivo setups. A high correlation between the scattering parameters of the proposed sensor and the variations in glucose levels is attained. Regression models are developed using experimental data obtained from healthy patients that are subjected to glucose tolerance tests. Results demonstrate less than 4% mean absolute relative difference between the reference and estimated glucose levels, and the predicted glucose levels lie 100% within the clinically acceptable zones as shown by the Clarke Error Grid analysis. |
| doi_str_mv | 10.1109/JERM.2020.3023053 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_RIE</sourceid><recordid>TN_cdi_crossref_primary_10_1109_JERM_2020_3023053</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><ieee_id>9190039</ieee_id><sourcerecordid>2530111670</sourcerecordid><originalsourceid>FETCH-LOGICAL-c293t-1419956064d2eaaebe783a83bf8b58768c90b9e6ab27eb7a7289d083d69f99a93</originalsourceid><addsrcrecordid>eNo9kMFOwkAQhjdGE4nyAMbLJp6Ls7ttt3NEAogBjSjnZrcdTEnt4m4h-vbSQDjNP8n3zyQfY3cCBkIAPr6Ml4uBBAkDBVJBoi5YT8YpRlom-vKcY7xm_RA2ACB0JjGOe-x9yF9dE82avQnVnvikpt_K1sSn9a5wgfjCNVXrfNV88Q9qgvN8FbrF8CfvTGlNU_Ilbaho-aSqW_K37Gpt6kD907xhq8n4c_Qczd-ms9FwHhUSVRuJWCAmKaRxKckYsqQzZTJl15lNMp1mBYJFSo2Vmqw2WmZYQqbKFNeIBtUNezje3Xr3s6PQ5hu3883hZS4TBUKIVMOBEkeq8C4ET-t866tv4_9yAXknL-_k5Z28_CTv0Lk_dioiOvMoEECh-geQwWlv</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2530111670</pqid></control><display><type>article</type><title>A Non-Invasive Flexible Glucose Monitoring Sensor Using a Broadband Reject Filter</title><source>IEEE Electronic Library (IEL)</source><creator>Bteich, Moussa ; Hanna, Jessica ; Costantine, Joseph ; Kanj, Rouwaida ; Tawk, Youssef ; Ramadan, Ali H. ; Eid, Assaad A.</creator><creatorcontrib>Bteich, Moussa ; Hanna, Jessica ; Costantine, Joseph ; Kanj, Rouwaida ; Tawk, Youssef ; Ramadan, Ali H. ; Eid, Assaad A.</creatorcontrib><description>In this paper, a novel, highly accurate, non-invasive glucose-monitoring sensor that is based on a flexible broadband reject filter is presented. The filter topology comprises a tapered feed line at a top layer that excites four open loop resonators on the bottom layer. The broadband reject response is achieved by relying on a modified log-periodic distribution of the open loop resonators. The embedded resonators are reduced in size and are designed to exhibit an enhanced sensitivity to track the variations of the glucose level across the 1.25-2.65 GHz frequency span. The proposed flexible filter is tested within in-vitro, ex-vivo and in-vivo setups. A high correlation between the scattering parameters of the proposed sensor and the variations in glucose levels is attained. Regression models are developed using experimental data obtained from healthy patients that are subjected to glucose tolerance tests. Results demonstrate less than 4% mean absolute relative difference between the reference and estimated glucose levels, and the predicted glucose levels lie 100% within the clinically acceptable zones as shown by the Clarke Error Grid analysis.</description><identifier>ISSN: 2469-7249</identifier><identifier>EISSN: 2469-7257</identifier><identifier>DOI: 10.1109/JERM.2020.3023053</identifier><identifier>CODEN: IJERLV</identifier><language>eng</language><publisher>Piscataway: IEEE</publisher><subject>Broadband ; Broadband communication ; Broadband reject filter ; Clarke error grid ; clinical trials ; dielectric characterization ; Error analysis ; Glucose ; Microwave filters ; Monitoring ; non-invasive glucose monitoring sensor ; Regression models ; Resonator filters ; Resonators ; Scattering parameters ; Sensitivity enhancement ; Sensors ; Sugar ; Topology</subject><ispartof>IEEE journal of electromagnetics, RF and microwaves in medicine and biology, 2021-06, Vol.5 (2), p.139-147</ispartof><rights>Copyright The Institute of Electrical and Electronics Engineers, Inc. (IEEE) 2021</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c293t-1419956064d2eaaebe783a83bf8b58768c90b9e6ab27eb7a7289d083d69f99a93</citedby><cites>FETCH-LOGICAL-c293t-1419956064d2eaaebe783a83bf8b58768c90b9e6ab27eb7a7289d083d69f99a93</cites><orcidid>0000-0002-7284-5956 ; 0000-0003-3423-5425 ; 0000-0002-3603-0960 ; 0000-0003-2955-1941 ; 0000-0002-7428-5067 ; 0000-0002-0571-1368 ; 0000-0002-3519-2917</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://ieeexplore.ieee.org/document/9190039$$EHTML$$P50$$Gieee$$H</linktohtml><link.rule.ids>314,780,784,796,27924,27925,54758</link.rule.ids><linktorsrc>$$Uhttps://ieeexplore.ieee.org/document/9190039$$EView_record_in_IEEE$$FView_record_in_$$GIEEE</linktorsrc></links><search><creatorcontrib>Bteich, Moussa</creatorcontrib><creatorcontrib>Hanna, Jessica</creatorcontrib><creatorcontrib>Costantine, Joseph</creatorcontrib><creatorcontrib>Kanj, Rouwaida</creatorcontrib><creatorcontrib>Tawk, Youssef</creatorcontrib><creatorcontrib>Ramadan, Ali H.</creatorcontrib><creatorcontrib>Eid, Assaad A.</creatorcontrib><title>A Non-Invasive Flexible Glucose Monitoring Sensor Using a Broadband Reject Filter</title><title>IEEE journal of electromagnetics, RF and microwaves in medicine and biology</title><addtitle>JERM</addtitle><description>In this paper, a novel, highly accurate, non-invasive glucose-monitoring sensor that is based on a flexible broadband reject filter is presented. The filter topology comprises a tapered feed line at a top layer that excites four open loop resonators on the bottom layer. The broadband reject response is achieved by relying on a modified log-periodic distribution of the open loop resonators. The embedded resonators are reduced in size and are designed to exhibit an enhanced sensitivity to track the variations of the glucose level across the 1.25-2.65 GHz frequency span. The proposed flexible filter is tested within in-vitro, ex-vivo and in-vivo setups. A high correlation between the scattering parameters of the proposed sensor and the variations in glucose levels is attained. Regression models are developed using experimental data obtained from healthy patients that are subjected to glucose tolerance tests. Results demonstrate less than 4% mean absolute relative difference between the reference and estimated glucose levels, and the predicted glucose levels lie 100% within the clinically acceptable zones as shown by the Clarke Error Grid analysis.</description><subject>Broadband</subject><subject>Broadband communication</subject><subject>Broadband reject filter</subject><subject>Clarke error grid</subject><subject>clinical trials</subject><subject>dielectric characterization</subject><subject>Error analysis</subject><subject>Glucose</subject><subject>Microwave filters</subject><subject>Monitoring</subject><subject>non-invasive glucose monitoring sensor</subject><subject>Regression models</subject><subject>Resonator filters</subject><subject>Resonators</subject><subject>Scattering parameters</subject><subject>Sensitivity enhancement</subject><subject>Sensors</subject><subject>Sugar</subject><subject>Topology</subject><issn>2469-7249</issn><issn>2469-7257</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>RIE</sourceid><recordid>eNo9kMFOwkAQhjdGE4nyAMbLJp6Ls7ttt3NEAogBjSjnZrcdTEnt4m4h-vbSQDjNP8n3zyQfY3cCBkIAPr6Ml4uBBAkDBVJBoi5YT8YpRlom-vKcY7xm_RA2ACB0JjGOe-x9yF9dE82avQnVnvikpt_K1sSn9a5wgfjCNVXrfNV88Q9qgvN8FbrF8CfvTGlNU_Ilbaho-aSqW_K37Gpt6kD907xhq8n4c_Qczd-ms9FwHhUSVRuJWCAmKaRxKckYsqQzZTJl15lNMp1mBYJFSo2Vmqw2WmZYQqbKFNeIBtUNezje3Xr3s6PQ5hu3883hZS4TBUKIVMOBEkeq8C4ET-t866tv4_9yAXknL-_k5Z28_CTv0Lk_dioiOvMoEECh-geQwWlv</recordid><startdate>20210601</startdate><enddate>20210601</enddate><creator>Bteich, Moussa</creator><creator>Hanna, Jessica</creator><creator>Costantine, Joseph</creator><creator>Kanj, Rouwaida</creator><creator>Tawk, Youssef</creator><creator>Ramadan, Ali H.</creator><creator>Eid, Assaad A.</creator><general>IEEE</general><general>The Institute of Electrical and Electronics Engineers, Inc. (IEEE)</general><scope>97E</scope><scope>RIA</scope><scope>RIE</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SP</scope><scope>8FD</scope><scope>L7M</scope><orcidid>https://orcid.org/0000-0002-7284-5956</orcidid><orcidid>https://orcid.org/0000-0003-3423-5425</orcidid><orcidid>https://orcid.org/0000-0002-3603-0960</orcidid><orcidid>https://orcid.org/0000-0003-2955-1941</orcidid><orcidid>https://orcid.org/0000-0002-7428-5067</orcidid><orcidid>https://orcid.org/0000-0002-0571-1368</orcidid><orcidid>https://orcid.org/0000-0002-3519-2917</orcidid></search><sort><creationdate>20210601</creationdate><title>A Non-Invasive Flexible Glucose Monitoring Sensor Using a Broadband Reject Filter</title><author>Bteich, Moussa ; Hanna, Jessica ; Costantine, Joseph ; Kanj, Rouwaida ; Tawk, Youssef ; Ramadan, Ali H. ; Eid, Assaad A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c293t-1419956064d2eaaebe783a83bf8b58768c90b9e6ab27eb7a7289d083d69f99a93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Broadband</topic><topic>Broadband communication</topic><topic>Broadband reject filter</topic><topic>Clarke error grid</topic><topic>clinical trials</topic><topic>dielectric characterization</topic><topic>Error analysis</topic><topic>Glucose</topic><topic>Microwave filters</topic><topic>Monitoring</topic><topic>non-invasive glucose monitoring sensor</topic><topic>Regression models</topic><topic>Resonator filters</topic><topic>Resonators</topic><topic>Scattering parameters</topic><topic>Sensitivity enhancement</topic><topic>Sensors</topic><topic>Sugar</topic><topic>Topology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bteich, Moussa</creatorcontrib><creatorcontrib>Hanna, Jessica</creatorcontrib><creatorcontrib>Costantine, Joseph</creatorcontrib><creatorcontrib>Kanj, Rouwaida</creatorcontrib><creatorcontrib>Tawk, Youssef</creatorcontrib><creatorcontrib>Ramadan, Ali H.</creatorcontrib><creatorcontrib>Eid, Assaad A.</creatorcontrib><collection>IEEE All-Society Periodicals Package (ASPP) 2005-present</collection><collection>IEEE All-Society Periodicals Package (ASPP) 1998-Present</collection><collection>IEEE Electronic Library (IEL)</collection><collection>CrossRef</collection><collection>Electronics & Communications Abstracts</collection><collection>Technology Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>IEEE journal of electromagnetics, RF and microwaves in medicine and biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Bteich, Moussa</au><au>Hanna, Jessica</au><au>Costantine, Joseph</au><au>Kanj, Rouwaida</au><au>Tawk, Youssef</au><au>Ramadan, Ali H.</au><au>Eid, Assaad A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Non-Invasive Flexible Glucose Monitoring Sensor Using a Broadband Reject Filter</atitle><jtitle>IEEE journal of electromagnetics, RF and microwaves in medicine and biology</jtitle><stitle>JERM</stitle><date>2021-06-01</date><risdate>2021</risdate><volume>5</volume><issue>2</issue><spage>139</spage><epage>147</epage><pages>139-147</pages><issn>2469-7249</issn><eissn>2469-7257</eissn><coden>IJERLV</coden><abstract>In this paper, a novel, highly accurate, non-invasive glucose-monitoring sensor that is based on a flexible broadband reject filter is presented. The filter topology comprises a tapered feed line at a top layer that excites four open loop resonators on the bottom layer. The broadband reject response is achieved by relying on a modified log-periodic distribution of the open loop resonators. The embedded resonators are reduced in size and are designed to exhibit an enhanced sensitivity to track the variations of the glucose level across the 1.25-2.65 GHz frequency span. The proposed flexible filter is tested within in-vitro, ex-vivo and in-vivo setups. A high correlation between the scattering parameters of the proposed sensor and the variations in glucose levels is attained. Regression models are developed using experimental data obtained from healthy patients that are subjected to glucose tolerance tests. Results demonstrate less than 4% mean absolute relative difference between the reference and estimated glucose levels, and the predicted glucose levels lie 100% within the clinically acceptable zones as shown by the Clarke Error Grid analysis.</abstract><cop>Piscataway</cop><pub>IEEE</pub><doi>10.1109/JERM.2020.3023053</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-7284-5956</orcidid><orcidid>https://orcid.org/0000-0003-3423-5425</orcidid><orcidid>https://orcid.org/0000-0002-3603-0960</orcidid><orcidid>https://orcid.org/0000-0003-2955-1941</orcidid><orcidid>https://orcid.org/0000-0002-7428-5067</orcidid><orcidid>https://orcid.org/0000-0002-0571-1368</orcidid><orcidid>https://orcid.org/0000-0002-3519-2917</orcidid></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | ISSN: 2469-7249 |
| ispartof | IEEE journal of electromagnetics, RF and microwaves in medicine and biology, 2021-06, Vol.5 (2), p.139-147 |
| issn | 2469-7249 2469-7257 |
| language | eng |
| recordid | cdi_crossref_primary_10_1109_JERM_2020_3023053 |
| source | IEEE Electronic Library (IEL) |
| subjects | Broadband Broadband communication Broadband reject filter Clarke error grid clinical trials dielectric characterization Error analysis Glucose Microwave filters Monitoring non-invasive glucose monitoring sensor Regression models Resonator filters Resonators Scattering parameters Sensitivity enhancement Sensors Sugar Topology |
| title | A Non-Invasive Flexible Glucose Monitoring Sensor Using a Broadband Reject Filter |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-26T13%3A45%3A12IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_RIE&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20Non-Invasive%20Flexible%20Glucose%20Monitoring%20Sensor%20Using%20a%20Broadband%20Reject%20Filter&rft.jtitle=IEEE%20journal%20of%20electromagnetics,%20RF%20and%20microwaves%20in%20medicine%20and%20biology&rft.au=Bteich,%20Moussa&rft.date=2021-06-01&rft.volume=5&rft.issue=2&rft.spage=139&rft.epage=147&rft.pages=139-147&rft.issn=2469-7249&rft.eissn=2469-7257&rft.coden=IJERLV&rft_id=info:doi/10.1109/JERM.2020.3023053&rft_dat=%3Cproquest_RIE%3E2530111670%3C/proquest_RIE%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2530111670&rft_id=info:pmid/&rft_ieee_id=9190039&rfr_iscdi=true |