The NDE1 genomic locus can affect treatment of psychiatric illness through gene expression changes related to microRNA-484

Genetic studies of familial schizophrenia in Finland have observed significant associations with a group of biologically related genes, DISC1, NDE1, NDEL1, PDE4B and PDE4D, the ‘DISC1 network’. Here, we use gene expression and psychoactive medication use data to study their biological consequences a...

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Veröffentlicht in:	Open biology 2017-11, Vol.7 (11), p.170153
Hauptverfasser:	Bradshaw, Nicholas J., Ukkola-Vuoti, Liisa, Pankakoski, Maiju, Zheutlin, Amanda B., Ortega-Alonso, Alfredo, Torniainen-Holm, Minna, Sinha, Vishal, Therman, Sebastian, Paunio, Tiina, Suvisaari, Jaana, Lönnqvist, Jouko, Cannon, Tyrone D., Haukka, Jari, Hennah, William
Format:	Artikel
Sprache:	eng
Schlagworte:	Disc1 Network Gene Expression Mir-484 Nde1 Pharmacogenetics Schizophrenia
Online-Zugang:	Volltext
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