lncRNAs in development and disease: from functions to mechanisms

Differential expression of long non-coding RNAs (lncRNAs) during differentiation and their misregulation in cancer highlight their potential as cell fate regulators. While some example lncRNAs have been characterized in great detail, the functional in vivo relevance of others has been called into qu...

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Veröffentlicht in:	Open biology 2017-07, Vol.7 (7), p.170121
Hauptverfasser:	Delás, M. Joaquina, Hannon, Gregory J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cancer Cell Transformation, Neoplastic - genetics Cell Transformation, Neoplastic - metabolism Chromatin - genetics Chromatin - metabolism Development Gene Expression Regulation, Developmental Genetic Association Studies Genetic Predisposition to Disease Humans Long Non-Coding Rnas Neoplasms - genetics Neoplasms - metabolism Organ Specificity - genetics Review RNA, Long Noncoding - genetics
Online-Zugang:	Volltext
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