Driver Gene Mutations and Epigenetics in Colorectal Cancer

OBJECTIVE:The majority of patients with colorectal cancer are diagnosed with locally advanced and/or disseminated disease, and treatment options include surgery in combination with cytotoxic chemotherapy regimens, biologics, and/or radiotherapy. Thus, colorectal cancer remains a heavy burden on soci...

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Veröffentlicht in:	Annals of surgery 2020-01, Vol.271 (1), p.75-85
Hauptverfasser:	Raskov, Hans, Søby, Jacob H., Troelsen, Jesper, Bojesen, Rasmus D., Gögenur, Ismail
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers, Tumor - genetics Colorectal Neoplasms - genetics Disease Progression DNA, Neoplasm - genetics Epigenesis, Genetic - genetics Humans Mutation
Online-Zugang:	Volltext
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