Deferoxamine Mitigates Radiation-Induced Tissue Injury in a Rat Irradiated TRAM Flap Model

Radiation therapy results in permanent damage to the microvasculature, leading to dermal damage and inelasticity in normal tissues. Deferoxamine is a U.S. Food and Drug Administration-approved iron-chelating medication that has also been shown to increase angiogenesis. The authors hypothesize that t...

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Veröffentlicht in:	Plastic and reconstructive surgery (1963) 2015-01, Vol.135 (1), p.124e-134e
Hauptverfasser:	Mericli, Alexander F., Das, Anusuya, Best, Ryan, Rodeheaver, Pamela, Rodeheaver, George, Lin, Kant Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Deferoxamine - therapeutic use Disease Models, Animal Male Radiation Injuries - drug therapy Rats Rats, Sprague-Dawley Rectus Abdominis - transplantation Surgical Flaps
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