Noninvasive Detection of Fetal Trisomy 21 by Sequencing of DNA in Maternal Blood: A Study in a Clinical Setting

The incidence of trisomy 21 in the general population is about 1 in 800 births. The risk of this chromosomal aneuploidy increases with age to 1 in 35 term births for women 45 years of age. The risk can increase substantially when advanced maternal age is integrated with other maternal risk factors,...

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Veröffentlicht in:	Obstetrical & gynecological survey 2011-06, Vol.66 (6), p.342-344
Hauptverfasser:	Ehrich, Mathias, Deciu, Cosmin, Zwiefelhofer, Tricia, Tynan, John A, Cagasan, Lesley, Tim, Roger, Lu, Vivian, McCullough, Ron, McCarthy, Erin, Nygren, Anders O. H, Dean, Jarrod, Tang, Lin, Hutchison, Don, Lu, Tim, Wang, Huiquan, Angkachatchai, Vach, Oeth, Paul, Cantor, Charles R, Bombard, Allan, van den Boom, Dirk
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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