Breast-Cancer Risk in Families With Mutations in PALB2

ABSTRACTGermline mutations in the BRCA1 and BRCA2 genes confer a marked increase in risk of breast cancer. Loss-of-function mutations have been identified in the PALB2 gene that also increase the risk of breast cancer. PALB2 interacts with BRCA1 and BRCA2 genes. In previous studies, the risk of brea...

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Veröffentlicht in:	Obstetrical & gynecological survey 2014-11, Vol.69 (11), p.659-660
Hauptverfasser:	Antoniou, Antonis C, Casadei, Silvia, Heikkinen, Tuomas, Barrowdale, Daniel, Pylkäs, Katri, Roberts, Jonathan, Lee, Andrew, Subramanian, Deepak, de Leeneer, Kim, Fostira, Florentia, Tomiak, Eva, Neuhausen, Susan L, Teo, Zhi L, Khan, Sofia, Aittomäki, Kristiina, Moilanen, Jukka S, Turnbull, Clare, Seal, Sheila, Mannermaa, Arto, Kallioniemi, Anne, Lindeman, Geoffrey J, Buys, Saundra S, Andrulis, Irene L, Radice, Paolo, Tondini, Carlo, Manoukian, Siranoush, Toland, Amanda E, Miron, Penelope, Weitzel, Jeffrey N, Domchek, Susan M, Poppe, Bruce, Claes, Kathleen B.M, Yannoukakos, Drakoulis, Concannon, Patrick, Bernstein, Jonine L, James, Paul A, Easton, Douglas F, Goldgar, David E, Hopper, John L, Rahman, Nazneen, Peterlongo, Paolo, Nevanlinna, Heli, King, Mary-Claire, Couch, Fergus J, Southey, Melissa C, Winqvist, Robert, Foulkes, William D, Tischkowitz, Marc
Format:	Artikel
Sprache:	eng
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